Protein Alignment mahe and DDX53

DIOPT Version :9

• Sequence 1: NP_001284994.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_874358.2
• Gene: DDX53 / 168400
• HGNCID: 20083
• Length: 631
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 216/614 - (35%)
• Similarity: 318/614 - (51%)
• Gaps: 102/614 - (16%)

  Fly   119 GSGGSGGYGGQRGKNPTYAQRYQKP------NNGAGVAGGYQSNNY------------------- 158
            |||.||.:|.|   .|..|...:.|      ||..||..||..:..
Human    29 GSGWSGPFGHQ---GPRAAGSREPPLCFKIKNNMVGVVIGYSGSKIKDLQHSTNTKIQIINGESE 90

  Fly   159 ---------------NAAALGMLSKEE---------RAEIQREKAKNPGRNLV------------ 187
                           .||...::.|:|         .|..|....:|.|||.:
Human    91 AKVRIFGNREMKAKAKAAIETLIRKQESYNSESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDR 155

  Fly   188 ---------KPKWENLEPFLKDFYNIHPNTLAKSEQQVAEIRRE-LEITV----SGNE--LPHPV 236
                     |.||.:|.|..|:||.....|...||.||...|:| ..||.    ||.:  :|.|.
Human   156 IRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPT 220

  Fly   237 VSFEES--SLPAHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHI 299
            ..|:::  ..| .:::.:.|.|..|||.||||.|||.|.|.||:.:||||:||||:|::|..:|:
Human   221 CRFKDAFQQYP-DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHL 284

  Fly   300 GNQPPIIRGE--GPIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVPQARDLDRG 362
            .:| ||.|.:  ||..|||.||||||..:::....|.:   ..::..||:||.::..|..|:.:|
Human   285 DSQ-PISREQRNGPGMLVLTPTRELALHVEAECSKYSY---KGLKSICIYGGRNRNGQIEDISKG 345

  Fly   363 VEVIIATPGRLIDFLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATW 427
            |::||||||||.|...|.:.||:..||||:||||:||||.||||||||:..:|||||.||.||||
Human   346 VDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410

  Fly   428 PKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGN 492
            |..|:.||..:|.|.:.:.:|::||.|.:.::|.:.:.||.||.......:..:||       .:
Human   411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP-------ND 468

  Fly   493 KIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDV 557
            |:|:||..|...:|:......:|.:|.|:||:..|::::..::||::|...|||.||:.|||||:
Human   469 KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDL 533

  Fly   558 EDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQTPSQALL 622
            .|:.:|.|||:|.:.:.||||:|..||..:.||:.|..|..::|.|.|||.:|:.|.|:..:.|:
Human   534 NDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLV 598

  Fly   623 DLARSMPSSGGYRGNKRWNNNSGGDRNTG 651
            .:|..      |:.|::..:.....|..|
Human   599 VMAEQ------YKLNQQKRHRETRSRKPG 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_001284994.1	PTZ00110	136..656	CDD:240273	208/597 (35%)
		DEADc	239..446	CDD:238167	102/210 (49%)
		HELICc	457..594	CDD:238034	47/136 (35%)
DDX53	NP_874358.2	KH-I	53..110	CDD:238053	8/56 (14%)
		Q motif	222..250		8/28 (29%)
		DEADc	231..428	CDD:238167	101/201 (50%)
		DEXDc	237..435	CDD:214692	101/201 (50%)
		DEAD box	376..379		2/2 (100%)
		HELICc	441..570	CDD:238034	47/135 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910