DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mahe and ddx59

DIOPT Version :9

Sequence 1:	NP_001284994.1	Gene:	mahe / 31707	FlyBaseID:	FBgn0029979	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	XP_031756897.1	Gene:	ddx59 / 100488709	XenbaseID:	XB-GENE-976229	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	434	Identity:	151/434 - (34%)
Similarity:	240/434 - (55%)	Gaps:	30/434 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 PFLKDFYNIHPNTLAKSEQQVAEIRRELEITVSGNELPHPVVSFEESSLPAHVIEEMKRQGFTKP 260
            |::   |..|......|..|:..:|::|.::|.|||:..|::.|:....|..:...:|..|:..|
Frog   332 PYI---YKEHEFISQLSADQINHLRQQLSLSVHGNEMCKPIMEFDHCQFPPVLSSNIKAAGYEVP 393

  Fly   261 TAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIRGEGPIALVLAPTRELAQQ 325
            |.||.|..|:.|.|||::..|.||||||.|::||||:..     :.:.:.|.||:|.||||||.|
Frog   394 TPIQMQMIPVGLMGRDILASADTGSGKTAAFLLPAIIRC-----LEKKDSPAALILTPTRELAVQ 453

  Fly   326 IQSVVRDYGHLCK--PEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFLENRNTNLQRCT 388
            |:...::   |.:  |.:|...:.||....||...|.:||:|||||||||::.::..:.||....
Frog   454 IEGQAKE---LMRGIPHMRTALLVGGMPLPPQIHRLKQGVQVIIATPGRLLEIIKQDSVNLGDLK 515

  Fly   389 YLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLS 453
            .|::||||.||.|||:.|:..|:|.:..|.|.::.|||.|..::|.....|.|.::|.:|..|..
Frog   516 ILIVDEADTMLKMGFQQQVLDILEVVPHDHQTILVSATIPAGIEAFTKQLLQDPVRITVGEKNQP 580

  Fly   454 ANHNIRQIVEICTEIEKPQRLVCLLNE---ISPIKNSGNNGNKIIVFVETKIKVEDILQ--IIRA 513
            .. |:||||....|..|.::|..:||:   ..|         .::|||:.::.. |:|.  :.:.
Frog   581 CT-NVRQIVLWVEEPSKKKKLFEILNDSKLFQP---------PVLVFVDCRLGA-DLLSDAVSKI 634

  Fly   514 EGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHR 578
            .|....::|.||:|.||..:|:....|:.:::::|.|..||||:.:::.|:|:|.|:|.:.|||:
Frog   635 TGLECVAMHSDKSQVERMKILQGLLQGEYDVVVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQ 699

  Fly   579 IGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQ-TPSQAL 621
            |||.||....|||.||...:|.....:|:..::..|. .|.|.|
Frog   700 IGRAGRLGHRGTAITFINKNNRNLFWDLVKRVQPTGSLLPPQLL 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_001284994.1	PTZ00110	136..656	CDD:240273	151/434 (35%)
		DEADc	239..446	CDD:238167	81/208 (39%)
		HELICc	457..594	CDD:238034	47/141 (33%)
ddx59	XP_031756897.1	PHA03247	<29..211	CDD:223021
ddx59	XP_031756897.1	PLN00206	217..759	CDD:215103	151/434 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910