Protein Alignment mahe and ddx46

DIOPT Version :10

• Sequence 1: NP_572424.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_002935944.1
• Gene: ddx46 / 100145307
• XenbaseID: XB-GENE-5787809
• Length: 1049
• Species: Xenopus tropicalis
• Alignment Length: 798
• Identity: 251/798 - (31%)
• Similarity: 372/798 - (46%)
• Gaps: 165/798 - (20%)

  Fly   162 ALGMLSKEERAEIQREKA--KNPGRNLVKP----KWENLEPFLKDFYNIHPNTLAKSEQQVAEIR 220
            |:...|:||..::|....  :...|.|::|    |.| .|.:.|:||...|.....:.::|...|
 Frog   290 AMEYSSEEEEVDLQTALTGFQTKQRKLLEPVDHGKIE-YESYRKNFYVEVPELAKMTTEEVNSYR 353

  Fly   221 RELE-ITVSGNELPHPVVSFEESSLPAHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTG 284
            .||| |||.|...|.|:.|:.:..:...::..:|:..:.|||.||:|..|..:|||||:|||:||
 Frog   354 LELEGITVKGKNCPKPIKSWVQCGISMKILNSLKKHAYEKPTPIQAQAIPAIMSGRDLIGIAKTG 418

  Fly   285 SGKTLAYMLPAIVHIGNQPPIIRGEGPIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGG 349
            ||||:|::||...||.:|.|:..||||||:::.||||||.||....:.:....  .:|..|::||
 Frog   419 SGKTIAFLLPMFRHIMDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKTL--GLRVVCVYGG 481

  Fly   350 SSKVPQARDLDRGVEVIIATPGRLIDFLENRN---TNLQRCTYLVLDEADRMLDMGFEPQIRKII 411
            :....|..:|.||.|:|:.||||:||.|...|   |||:|.||:||||||||.|||||||:.:||
 Frog   482 TGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRII 546

  Fly   412 EQIRPDRQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVC 476
            :.||||||.||:|||:|:.::|||...|:..|::.:|..::..: ::.|.|.:   ||:.::.:.
 Frog   547 DNIRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCS-DVEQHVIV---IEEEKKFLK 607

  Fly   477 LLNEISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGK 541
            ||..:...:..|    .:|:||:.:...:.:|:.:....|...|:||...|.:|||::.||:||.
 Frog   608 LLELLGHYQEKG----AVIIFVDKQEHADGLLKDLMRASYPCLSLHGGIDQYDRDSIINDFKNGV 668

  Fly   542 SNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQAREL 606
            ..:|:||.||:|||||:.|..||||..||..|:||||.|||||....|.|:||.|.|.|:.|.::
 Frog   669 CKLLVATSVAARGLDVKQLILVINYACPNHYEDYVHRAGRTGRAGNKGYAFTFITEDQARYAGDI 733

  Fly   607 ISVLEEAGQTPSQALLDLARSMPSSGGYRGNKRWN-----NNSGGD--RNTGGNNGIYQQRNNNP 664
            |..||.:|......|..|               ||     ..:.|.  :.|.|.:|
 Frog   734 IKALELSGTAVPAELEQL---------------WNEFKEQQKAEGKIIKKTSGFSG--------- 774

  Fly   665 LNYQAGNNYNNNRSGPPTGSSYQQYAAGGNTYLQNGAGGGV-------------NWNRMNQMGQD 716
                .|..::.............|.||.|   ||:......             :..|:..|...
 Frog   775 ----KGFKFDETEQALANERKKLQKAALG---LQDSDDEDTALDIDEQIESMFNSKKRVKDMAGP 832

  Fly   717 GGAGQQQRNGNTYRPRAPFNNGGPRAIMGHQGGGVGAGGAA------------------------ 757
            |||..               .|.|    |..||.||||.:|
 Frog   833 GGAAA---------------TGAP----GMVGGAVGAGSSANATLPTAGNAEKLEIAKRLAKKLS 878

  Fly   758 ---GVGGGPQQLM-----APQQGG-------------QYMPQAYRGRSQFVP--------QGAGA 793
               .:|...|.:|     |..:||             :.:.:....:..:||        |.|||
 Frog   879 VNKNLGAEAQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPVEKLEEEKQDAGA 943

  Fly   794 GGMPPRFQQYPK----REYQQQG---VTHYGQQALQHQQQQQQA-----GQQTKPPKD----ESN 842
            .   ..|::|.:    .::.|..   ||  .::|||...:..:|     |....|.||    |..
 Frog   944 N---ESFKRYEEELEINDFPQTARWKVT--SKEALQRISEYSEAAITIRGTYFPPGKDPKEGERK 1003

  Fly   843 KYVPSAAVTSSLVQYTPA 860
            .|:...:.:...||...|
 Frog  1004 IYLAIESASELAVQKAKA 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_572424.1	DEAD-like_helicase_N	136..656	CDD:475120	198/510 (39%)
ddx46	XP_002935944.1	DEADc_DDX46	360..581	CDD:350711	107/222 (48%)
		SrmB	377..792	CDD:440279	173/452 (38%)
		KH-I_DDX46	946..1048	CDD:411901	18/78 (23%)