DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ykt6 and VAMP7

DIOPT Version :9

Sequence 1:	NP_572423.1	Gene:	Ykt6 / 31706	FlyBaseID:	FBgn0260858	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001172112.1	Gene:	VAMP7 / 6845	HGNCID:	11486	Length:	260	Species:	Homo sapiens

Alignment Length:	149	Identity:	27/149 - (18%)
Similarity:	53/149 - (35%)	Gaps:	27/149 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FSFFQRGTV---------NEFMTFASKTIVERTQPALRQSVKQDAYMCHVYVRADNLAGVLIADH 84
            |:...|||.         ..|:....:.:.:......:.:.....|:.| |:..|.:..:.|.|.
Human     5 FAVVARGTTILAKHAWCGGNFLEVTEQILAKIPSENNKLTYSHGNYLFH-YICQDRIVYLCITDD 68

  Fly    85 EYPHRVAHTLITKILDDFTAKVSADQWPNGTEATISF---------DLLPAFLARYQNPVEADPL 140
            ::....|...:.:|...|       |...|:.|..:.         .:|.|.|..:......|.:
Human    69 DFERSRAFNFLNEIKKRF-------QTTYGSRAQTALPYAMNSEFSSVLAAQLKHHSENKGLDKV 126

  Fly   141 TKMQNDLDETK-IILKNTI 158
            .:.|..:||.| |:::|.:
Human   127 METQAQVDELKGIMVRNIV 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ykt6	NP_572423.1	SNC1	4..196	CDD:227472	27/149 (18%)
VAMP7	NP_001172112.1	Longin	29..104	CDD:316307	12/82 (15%)
VAMP7	NP_001172112.1	SNARE	124..>144	CDD:328933	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810