Protein Alignment hdm and meiob

DIOPT Version :10

• Sequence 1: NP_572422.1
• Gene: hdm / 31705
• FlyBaseID: FBgn0029977
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_068074771.1
• Gene: meiob / 101882335
• ZFINID: ZDB-GENE-120104-8
• Length: 466
• Species: Danio rerio
• Alignment Length: 491
• Identity: 133/491 - (27%)
• Similarity: 221/491 - (45%)
• Gaps: 67/491 - (13%)

  Fly    10 LAEMRPTMTRFSTVALIVSKSSPNIFYDKMS-GTERGVLSLTIRDSPNHLTNCKCWGQRDCVDEY 73
            ::::...:|....|.:|:.|:....|.|:.: |:||...|.||:|||.|..|...||..:.:...
Zfish    12 ISDLNINITHSKVVGVIIGKTDSRGFPDRKNVGSERFTFSFTIKDSPEHFINVSAWGNEEYIQAL 76

  Fly    74 AAMLQIGHVVDIVGAKVMSIPFAAPGEQRYQPQATVSCALVVNE-GSGYVVRHDNDDFGQITILQ 137
            :...|||..|.|....|::..:..  |:|:.|....|..|::.| .|...:..|.|...:|.
Zfish    77 SCRFQIGDCVVIENPLVVTKDYEK--EERFCPSTPSSYRLLLTETHSSIRICSDIDTEARIL--- 136

  Fly   138 QLLHQPIRPLGAVLKLADV-RSGLGFPDKIITTNVNLLVVVAAVRPVRQIK--RKLQGPLSEVQE 199
            .|.|.||:.......|.|: .:|......:|.       ::|||:.|.:.|  .|..|...
Zfish   137 PLFHIPIKDPRDFYSLGDITANGQSLDGHVIN-------ILAAVQSVGEEKFFTKSGGCKG---- 190

  Fly   200 LLQCLEVIVID---ASYPEGMLLSVWQPDWIQRAQQWQPRRTVLHLIDVRVSYSNFHRSLVLSHS 261
              |.:|:.:.|   .|:|    ...|..:.|:..|....|.|||.:.|.|:::.:|.:|:|.:..
Zfish   191 --QRIEIKLFDDTGRSFP----FVCWDKENIRLVQTLTQRETVLFIADARITFDSFRKSMVATAI 249

  Fly   262 NCTLICENPQAAGDDCRLLLAFAATVPLTTFSGCDQAEL---DNMPAVASIQAQMTVRQIYSRAE 323
            :.|:|..||..|  :...|..|..  .|....|.|..:.   |:: .:.||:..|||.|:.:|::
Zfish   250 SKTIITVNPDTA--EANQLYTFVR--ELLQSGGLDDQDFLSGDDV-LLDSIRDVMTVSQLKTRSQ 309

  Fly   324 GELQDPSIHQFTAVLYGMVTKFDLDGLTSH-VNRKCIACQQHIPRNLQDCASDACQQYFSLDNDE 387
             |..| :||   .::||.:|.|||....|. :.::|..|:..|......|:||.|..    ...|
Zfish   310 -ENAD-AIH---CIIYGFITCFDLGSSPSKIITKRCARCKFRINEESWTCSSDICPN----QGQE 365

  Fly   388 PRSISYFNINIHLSDQTGTLVEARLAGHPAERILGLRAEDFERLAEREKSELKWRFLLKYFEVRL 452
            .::...|::.:.:||.||||....|.|..||:.||.:.|:|..|:|.:::.|:|:|||:..::.|
Zfish   366 LQANECFDVLVDISDHTGTLQSCNLVGTVAEKTLGCKTEEFLCLSEYQRTSLQWKFLLERCKIYL 430

  Fly   453 MI-------------------KKPVGVRNHLVIVVV 469
            .:                   ..||.|:.:|...||
Zfish   431 KVLPSPRRRSGMKADILSCGLADPVEVKQNLASFVV 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hdm	NP_572422.1	None
meiob	XP_068074771.1	RFA1	10..>93	CDD:441207	24/80 (30%)
		rpa1	<112..427	CDD:273177	97/348 (28%)
		Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.	166..266	CDD:471953	30/118 (25%)