Protein Alignment snz and snx25

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_001156765.1
• Gene: snx25 / 793657
• ZFINID: ZDB-GENE-121105-11
• Length: 961
• Species: Danio rerio
• Alignment Length: 998
• Identity: 317/998 - (31%)
• Similarity: 518/998 - (51%)
• Gaps: 129/998 - (12%)

  Fly    54 GITLTLLAVIWYYPTFFL-FFAFVVYSLVLVFAAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNAT 117
            |:.||         :||| .|.:|.::|   |..:.|:      |.......|.|: ||  ::.|
Zfish    44 GLGLT---------SFFLKLFIYVSFAL---FCFLLGS------FGLLVKKSPLRI-SR--FDTT 87

  Fly   118 K---SNIFDLPKPIKNPSNLPL---------IFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPK 170
            |   ..:.||...:.....:||         :....||..|:::.:|..||::|.|...:.....
Zfish    88 KRQSDKLVDLFNKLMGRFCVPLLDSAQTRRVVVSLNVDKALKEVFDYSYRDYILSWYVPLSRDEG 152

  Fly   171 LINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVFSTNS 235
            .:..::.||.|..|:::..|...:|...::..|||..:..|...::.|..|..|...|  |..:.
Zfish   153 QLYQMLSEDFWEMIKQVRMRLSEVDVVNLVCNDMVKTLHQHFCDLKAANTRLEEVPRP--FPLHP 215

  Fly   236 YLADEEKEMEFLRKLCEIMVILLLP-RGYSLPPLKVLLSEILSYKIFFPMIKMLTAPDYINQKVV 299
            .|...::|:.|||....::::.||| |......|::||.|:::.|:..|::.:|:.|||||:.::
Zfish   216 CLQSPDEELRFLRCCARLLLLRLLPVRDARSRSLRLLLVEVVTTKVLKPLVDVLSDPDYINRMLL 280

  Fly   300 QNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQN---LQRA 361
            ..:|.|.......|::|.||.|:|:|:|:|::|..::.|..:|..||.:::.|||:.:   |:|.
Zfish   281 AQLEHREQVNEHHKKAYTYAPSYEEFIKLISSSSGIQFLKQLRYQIVVEIIQATTISSIPQLKRQ 345

  Fly   362 KGLDPDHEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNYSSDID---------- 416
            |  |...::.:..|::|..|..:|||:.|||:||.:|||.:...| ..||....|
Zfish   346 K--DSKGKEAAALKADLLRARNMKRYINQLTVAKKQCEKRIRLLG-GPNYEQQEDGGQEEGDGPQ 407

  Fly   417 ----LTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVP 477
                |...||::.:|.|.:|.:::|.:...|||.|:..||.:|.|:|:...||..||:..:. |.
Zfish   408 SQRILQFEEIMSNSVYRDHFRVYMERVDKRALISFWELVEMLKTANKNEVPQLVGEIYQNFF-VE 471

  Fly   478 KSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYPPFVLSDQYRQL-------KEA 535
            ..||.::|...|.|:..|:|:...|:|:.||.:|..|::|:|||.|::||.|.:|       ..:
Zfish   472 SREIPVEKALYKEIQQTLVGNKGTDVFHRIQGDVYETMKERYYPSFLVSDLYERLIKREEQRSSS 536

  Fly   536 LDSNEIADPTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERIDK 600
            ..|:|..|.|       |.|.|       |....|:.|:.|   :....|||..||.|:.||::.
Zfish   537 QSSSEEKDDT-------GQVME-------GGDVALDEGSKG---INEQASYAATKLHQLYERLEY 584

  Fly   601 KNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDE 665
            |.|||.:::.:.:|:.|::::|:.|:..::.|....|.|:.|||.|.|:||.|:|.:.:.|.|:|
Zfish   585 KRQALGSIQNAPRPDKKIVSLLKDEISAMEKEHSDLELHISRTDCWCENLGTWRAVVSTAEASEE 649

  Fly   666 --KESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLR 728
              ::...:.:.|.:.|:       ...||                :.|.|.|.|.:...|.|||.
Zfish   650 NGEQMACYFVAVSLSEE-------DDCKN----------------NHWTVSRKLIEFQALHRKLT 691

  Fly   729 HVSSNLKAIDLPTNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSDHLK 793
            ....:||.:.||:..|..|...|:...:|:|:|:..||..:|.|:.:..|||:|.|||||.:|||
Zfish   692 ECFPSLKKVQLPSLSKLPFKSIDQKFLDKSKNQLNAFLQKVLTDERMCQSEALYAFLSPSPEHLK 756

  Fly   794 QSLPSPKKSKFSLSTLFRSDAGK--AHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADL 856
             .:...|||.|||::......|.  :|:..:|        .||.|:|.|.|...|
Zfish   757 -VIDIQKKSSFSLASFLERLPGDFFSHQEDEA--------EDDSDLSDYGDEPDG---------- 802

  Fly   857 DSKDSIAEPMYALMGEIFDMGGVFKWLRKSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFS 921
             .||::|||.:.|:||||::.|:|||:||:||:.||:|:|||||:|||::|.::|.|.|:..|.:
Zfish   803 -KKDALAEPCFMLIGEIFELRGMFKWVRKTLIALVQVTFGRTINKQIRDTVNWIFSEQMMVYYIN 866

  Fly   922 AILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQN 986
            ....:|||.|.||....:|.|..|..|...|:..|.|:||:.|.||||.|.|:.|::|:|:|||.
Zfish   867 VFRDTFWPNGKLAPHNKSRCESERRETKERAQQKLLDNIPDALQNLVGQQNARYGIIKIFNALQE 931

  Fly   987 PAYNKQLFYELLEILMIEFFPEI 1009
            .:.|:.|.|.|||:|:.|.:.|:
Zfish   932 SSANRHLLYMLLEMLVKELYAEL 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	44/158 (28%)
		RGS_SNX25	422..531	CDD:188675	40/108 (37%)
		PX_SNX25	645..788	CDD:132788	42/144 (29%)
		Nexin_C	882..987	CDD:462541	49/104 (47%)
snx25	NP_001156765.1	PXA	124..280	CDD:460484	44/157 (28%)
		RGS	417..525	CDD:470619	40/108 (37%)
		PX_SNX25	630..751	CDD:132788	42/143 (29%)
		Nexin_C	827..930	CDD:462541	47/102 (46%)