DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snz and Snx16

DIOPT Version :9

Sequence 1:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	NP_083344.3	Gene:	Snx16 / 74718	MGIID:	1921968	Length:	344	Species:	Mus musculus

Alignment Length:	373	Identity:	67/373 - (17%)
Similarity:	117/373 - (31%)	Gaps:	138/373 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   555 VQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRKLE----------QIQERIDKKNQAL---- 605
            |..|:.:......:..|..:.....|:..::.::.:||          .:|:::|..:...
Mouse     8 VPMPIGNSASSFTNNRNQRSSSFGSVSTSSTSSKGQLEDSAVGSLKQTNVQDQMDSASSMCGSPL 72

  Fly   606 ---------DALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWK-----AT 656
                     .:::||.:|.              ::|::..||            ..|:     .|
Mouse    73 IRTKFTGTDSSIEYSARPR--------------EAEEQHPEA------------VNWEDRPSTPT 111

  Fly   657 IQSVEVSDEKESLQ-FMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQV 720
            |...||.:|:.... :.|||                         :|.|   ...|||.|.....
Mouse   112 ILGYEVMEERAKFTVYKILV-------------------------KKSP---EESWVVFRRYTDF 148

  Fly   721 HELQRKLRHVSSNLKAIDLP------TNFKFFFLKTDRHGQEKAKSQIQKFL-NFI--------- 769
            ..|..||:.:....: :.||      .|:...||:..:.|       :|.|| |.:
Mouse   149 SRLNDKLKEMFPGFR-LALPPKRWFKDNYNAEFLEDRQLG-------LQAFLQNLVAHKDIANCL 205

  Fly   770 -------LED-----DHLNGSEAIYTFLSPSSDHLKQSLPSPKKSKFSLSTL-----FRSDAGKA 817
                   |:|     |.|..|.|....|..::.||::.|...:|...||..|     ...||.:.
Mouse   206 AVREFLCLDDPPGPFDSLEESRAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALET 270

  Fly   818 HEASKATDPFWGLQRDDEDISTYLDGESGG-----EAKMLAADLDSKD 860
            ...:.:.:|         ..|.|:....||     |..:|..:.|..|
Mouse   271 RIRTLSLEP---------GASLYVSRAEGGQILRVEPSVLQVNRDVLD 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788	35/176 (20%)
		Nexin_C	882..987	CDD:285792
Snx16	NP_083344.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..72		8/63 (13%)
Snx16	NP_083344.3	PX_SNX16	105..214	CDD:132809	27/144 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900