DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snz and Snx20

DIOPT Version :9

Sequence 1:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	NP_082116.1	Gene:	Snx20 / 71607	MGIID:	1918857	Length:	313	Species:	Mus musculus

Alignment Length:	238	Identity:	50/238 - (21%)
Similarity:	77/238 - (32%)	Gaps:	90/238 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 RYVRQLTMAKGECEKNLAKFGW-------NGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASA 443
            |.:.::..|:.| |:.::||..       .|::.||         ...|.|||..  .|.|:.:.
Mouse    72 RLLFEIASARIE-ERKVSKFVMYQVVVIQTGSFDSD---------KAVVERRYSD--FERLQKAL 124

  Fly   444 LIGFYLAVEEIKHAHKSASHQLGTE--------------IFYTYIRVPKSEIQIDKHER-KLIET 493
            |..|...:|::....|..:..|..|              :.|....|.:|...:|...| :|.|.
Mouse   125 LKRFGPELEDVAFPRKRLTGNLSAETICERRRELREYLRLLYAVRAVRRSREFLDFLTRPELREA 189

  Fly   494 F-------------LLGDAEP---------------------DIFYDIQR------------NVL 512
            |             |||.|.|                     ....|::|            ..|
Mouse   190 FGCLRAGQYARALELLGRALPLQEKLTAHCPSAAVPALCAALVCLRDLERPAEAFAVGERALRCL 254

  Fly   513 RTLE-EKYYPP---------FVLSDQYRQLKEALDSNEIADPT 545
            ||.| .:||.|         :.|...:..|:..||.|::..||
Mouse   255 RTRENHRYYAPLLDAMVRLAYALGKDFAALQSRLDENQLRRPT 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373
		RGS_SNX25	422..531	CDD:188675	35/179 (20%)
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:285792
Snx20	NP_082116.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..60
Snx20	NP_082116.1	PX_domain	73..186	CDD:383026	25/124 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900