DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snz and Snx16

DIOPT Version :9

Sequence 1:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	NP_071625.2	Gene:	Snx16 / 64088	RGDID:	620295	Length:	344	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	64/353 - (18%)
Similarity:	111/353 - (31%)	Gaps:	127/353 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   555 VQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRKLE----------QIQERIDKKNQAL---- 605
            |..|:.:......:..|..:.....|:..::.::.:||          .:|:::|..:...
  Rat     8 VPMPIGNSASSFTNNRNQRSSSFGSVSTSSNSSKGQLEDSSVGTCKHTNVQDQMDSASSVCGSPL 72

  Fly   606 ---------DALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDA--WTEHLGKWKATIQS 659
                     .:::||.:|                   |.||.  :..||  |.:...  ..||..
  Rat    73 IRTKFTGTDSSIEYSARP-------------------RDTEE--QHPDALNWEDRPS--TPTILG 114

  Fly   660 VEVSDEKESLQ-FMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHEL 723
            .||.:|:.... :.|||                         ::.|   ...|||.|.......|
  Rat   115 YEVMEERAKFTVYKILV-------------------------KESP---EESWVVFRRYTDFSRL 151

  Fly   724 QRKLRHVSSNLKAIDLP------TNFKFFFLKTDRHGQEKAKSQIQKFL-NFI------------ 769
            ..||:.:....: :.||      .|:...||:..:.|       :|.|| |.:
  Rat   152 NDKLKEMFPGFR-LALPPKRWFKDNYNADFLEDRQLG-------LQAFLQNLVAHKDIANCLAVR 208

  Fly   770 ----LED-----DHLNGSEAIYTFLSPSSDHLKQSLPSPKKSKFSLSTL-----FRSDAGKAHEA 820
                |:|     |.|..|.|....|..::.||::.|...:|...||..|     ...||.:....
  Rat   209 EFLCLDDPPGPFDSLEESRAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALETRIR 273

  Fly   821 SKATDPFWGLQRDDEDISTYLDGESGGE 848
            :.:.:|         ..|.|:....||:
  Rat   274 TLSLEP---------GASLYVSRAEGGQ 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788	35/173 (20%)
		Nexin_C	882..987	CDD:285792
Snx16	NP_071625.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		6/40 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	83..105		9/42 (21%)
		PX_SNX16	105..214	CDD:132809	26/146 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900