DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snz and sgk3

DIOPT Version :9

Sequence 1:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	NP_001103937.1	Gene:	sgk3 / 564523	ZFINID:	ZDB-GENE-070424-62	Length:	486	Species:	Danio rerio

Alignment Length:	376	Identity:	78/376 - (20%)
Similarity:	131/376 - (34%)	Gaps:	132/376 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   678 DEDINAPVQPTSSKNGDSG-HANLRKRPSGI---------SSGWVVMRSLNQ------VHELQRK 726
            |||..:   .::|:|.:.| .||...:|:..         |.|.|::....:      :..||:|
Zfish   125 DEDDKS---NSTSRNINLGPSANPHAKPTDFDFLKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKK 186

  Fly   727 L-------RHVSSN----LKAIDLP--TNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGS 778
            :       :|:.:.    ||.:..|  ....:.|..||:             |.|:|  |.:||.
Zfish   187 VILNRREQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDK-------------LYFVL--DFVNGG 236

  Fly   779 EAIYTFLSPSSDHL--KQSLPSPKKSKFSLSTLFRSDAGKAHEASKATDPFWGLQRDDEDISTYL 841
            |..:        ||  :::.|.| ::||.::.: .|..|..|..:.       :.||.:..:..|
Zfish   237 ELFF--------HLQKERTFPEP-RAKFYIAEM-ASALGYLHSLNI-------VYRDLKPENILL 284

  Fly   842 DGESGGEAKMLAADLD-SKDSIAE----------PMYALMGEIFDMGGVFKWLRKSLISFVQITY 895
            |    .:..::..|.. .|:.|::          |.| |..|:         |||.       .|
Zfish   285 D----SQGHIVLTDFGLCKEGISQADTTTTFCGTPEY-LAPEV---------LRKQ-------PY 328

  Fly   896 GRTINRQIRESVAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHI 960
            ..|::.....||.|    .||:.     |..|:            |.|..||         .|:|
Zfish   329 DNTVDWWCLGSVLY----EMLYG-----LPPFY------------SRDTHEM---------YDNI 363

  Fly   961 PEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFY--ELLEILMIEFFPEI 1009
              :...||....|......:...|....:.::|.|  :..|:...|||..|
Zfish   364 --LHKELVMRPGASTAAWSILQTLLEKDHTRRLGYRDDFNEVKEHEFFSSI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788	29/138 (21%)
		Nexin_C	882..987	CDD:285792	22/104 (21%)
sgk3	NP_001103937.1	PX_CISK	6..114	CDD:132780
		S_TKc	152..409	CDD:214567	66/341 (19%)
		STKc_SGK3	155..480	CDD:270755	69/343 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900