DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment snz and pxk

DIOPT Version :9

Sequence 1:NP_001284993.1 Gene:snz / 31704 FlyBaseID:FBgn0029976 Length:1117 Species:Drosophila melanogaster
Sequence 2:NP_001076277.1 Gene:pxk / 557065 ZFINID:ZDB-GENE-050208-393 Length:575 Species:Danio rerio


Alignment Length:434 Identity:87/434 - (20%)
Similarity:157/434 - (36%) Gaps:114/434 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   681 INAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPTNFKF 745
            ::|.::.:.|....:.:....:|.....:.|.|:|..:....|...|.     :..::||...|.
Zfish    24 LSAVIEASQSLQSHTEYIIRVQRGVSTDNSWTVIRRYSDFDMLNNSLL-----ISGLNLPLPPKK 83

  Fly   746 FFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSP---SSDHLKQSLPSPKKSKFSLS 807
            .....||....:.:..:|.:||:|.:...|...|.:..||..   |:::.:.:|.       .:|
Zfish    84 LLGNMDREFIAERQKGLQAYLNYITQHHILCSCELVKKFLDTNNYSANYTEIALQ-------QVS 141

  Fly   808 TLFRSDAGKAHEASKATDPFWGLQR-----DDED------ISTYLDGESGGEAKMLA-ADLD--- 857
            ..||||. |........|..|.|::     .|:|      :.:::|   .|..|.|: .||.   
Zfish   142 MFFRSDP-KWEVIEPLKDIGWRLRKRYFLVKDKDQPKEKQVLSWVD---LGPDKFLSDKDLQSAM 202

  Fly   858 ------SKDSIAEPMYALMGE-------IFDMGGVFK-----------WLRK----SLISFVQIT 894
                  |..:|:...:|...|       :|...|..:           :|||    ..|..:::.
Zfish   203 KLLPTLSHSNISPVSFATTSESSALIIRVFSEKGTLRDHICKVKPKEPFLRKYCNPKKIQGLELQ 267

  Fly   895 YGRTINRQIRESVAYLFEESMLHNYFSAI-------------LKSFWPGGVLASAYPTRSEDMRE 946
            ..||..|||.|::.:|.::...:.:..|.             :::...|  |.|.|.......|:
Zfish   268 QIRTFGRQILEALKFLHDKGFPYGHLHASNVLIEENTCKLLDVENSLLG--LPSYYRPYVTQFRK 330

  Fly   947 MTTTAA-------------------KALLTDHIP--------EVLCNLVGAQAAKRGVLKVFDAL 984
            :.||.:                   .|:..|..|        .||.:::..:|.|.|:..|...|
Zfish   331 INTTESIDVYSFGHLLYEMTYGRPPDAVPVDQCPPAPFSSIVSVLQSILSTEACKTGMPTVSQLL 395

  Fly   985 QNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTATAG 1028
            |.|     |||::|     .|..|..|.::|:.....|.::..|
Zfish   396 QTP-----LFYDVL-----LFNSEKPQFKISSKLKEALKSSKEG 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snzNP_001284993.1 PXA 142..299 CDD:280373
RGS_SNX25 422..531 CDD:188675
PX_SNX25 645..788 CDD:132788 21/109 (19%)
Nexin_C 882..987 CDD:285792 30/148 (20%)
pxkNP_001076277.1 PX_MONaKA 17..136 CDD:132781 22/116 (19%)
PKc_like 193..395 CDD:304357 37/203 (18%)
WH2 544..571 CDD:280384
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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