Protein Alignment snz and Snx13

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_006240084.1
• Gene: Snx13 / 362731
• RGDID: 1309778
• Length: 1144
• Species: Rattus norvegicus
• Alignment Length: 1083
• Identity: 248/1083 - (22%)
• Similarity: 403/1083 - (37%)
• Gaps: 294/1083 - (27%)

  Fly    60 LAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNE------------PTPPS------ 106
            |.::.:..||..|..|.:...:|.|......|.:.|..|.:|            ||.|.
  Rat   191 LGIVLFLITFGPFVIFYLAFYILCFVGGGLVVTLLYGKTNSEKYLEQCEHSFLPPTSPGVPKCLE 255

  Fly   107 ---------RVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWL 162
                     ::..||    |.:||.|.|                    |||:|::.|||::..|.
  Rat   256 EMKREARTIKIDRRL----TGANIIDEP--------------------LQQVIQFSLRDYVQYWY 296

  Fly   163 GYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNT 227
             |.::..:.....:|:.|.||:.:...|:..:|........||:....||...|.|:.|..|.:
  Rat   297 -YTLSDDETFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRMVDDFGTHLRVFRKAQQRVTEKD- 359

  Fly   228 PPVFSTNSYLADE----EKEME-----------------FLRKLCEIMVILLLPRG-YSLPPLKV 270
            ..|..|...|.:.    |.|||                 |||.|||:::.||||.| :....::.
  Rat   360 DQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQSKIMRY 424

  Fly   271 LLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNL 335
            .:.|||:..|..|:|..|:.||||||.|:..|.             :...::|.|:.||..|.|:
  Rat   425 FVREILARGILLPLINQLSDPDYINQYVIWMIR-------------DSNCNYEAFMNIIKLSDNI 476

  Fly   336 EELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRY----VRQLTMAKG 396
            .||..:|..         ..:.||..:.||...:|.:..|:::.:.:.:|:.    :::|...|
  Rat   477 GELEAVRDK---------AAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGK- 531

  Fly   397 ECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSA 461
              |.|..|..  .|:.....:.|..||...|..::|..:::.....|.:.|::.||..:   .:|
  Rat   532 --EINTVKLA--ANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYR---VTA 589

  Fly   462 SHQL------------------------GTEIFYTYIRVPKS-EIQIDKH-ERKLIETFLLGDAE 500
            ..||                        ...|:..|:....| .:.:|.: ..||.:|....|..
  Rat   590 QQQLEVLSSRQRDGKQQTNQTKGLLRAAAVGIYEQYLSEKASPRVIVDDYLVAKLADTLNHEDPT 654

  Fly   501 PDIFYDIQRNV--LRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQ 563
            |:||.||||.|  |...:|::||.|..:..|.::...||.  :.||:             .....
  Rat   655 PEIFDDIQRKVYELMLRDERFYPSFRQNPLYVRMLAELDM--LKDPS-------------FRGSD 704

  Fly   564 PGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEW 628
            .|..:..||...|:|                       |.:||.|. ||..:..|
  Rat   705 DGDGESFNGSPTGSI-----------------------NLSLDDLS-SVTSDDSV---------- 735

  Fly   629 LKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNG 693
                  |..|::..|                               |:.|.|..|    .:....
  Rat   736 ------QLHAYISDT-------------------------------VYADYDPYA----VAGVCN 759

  Fly   694 DSGHA------NLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAI-DLPTNFKFFFLKTD 751
            |.|..      .:.:|.......|...|..:..|:...::.....||.:| .||.  |..|...|
  Rat   760 DHGKTYALYAITVHRRSLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSILKLPG--KKTFNNMD 822

  Fly   752 RHGQEKAKSQIQKFLNFILEDDHLNGSEA----IY--------------------TFLSPSSDHL 792
            |...||.|..:..:|..:|..:.|..|.|    :|                    ||::|..:.:
  Rat   823 RDFLEKRKKDLNAYLQLLLTPEMLKASPALAHCVYDFLENKAYSKGKGDFARKMDTFVNPLRNSM 887

  Fly   793 KQSLPSPKKSKFSLS---TLFRSDAGKAHEASKATDPFWGLQRDDEDIS----------TYLDGE 844
            :....:.|....||:   |....:.|:..|            |..:||.          |..|
  Rat   888 RNVSNAVKSLPDSLAEGVTKMSDNVGRMSE------------RLGQDIKQSFFKVPPLITKTD-- 938

  Fly   845 SGGEAKMLAADLDSK--DSI-AEPMYALMGEIFDMGGVFKWLRKSLISFVQ----ITYGRTINRQ 902
            |..|...::|.||..  |:| ...|..||.|:||:....:|||:::.:.:|    .|||.||||:
  Rat   939 SDPEHCRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRK 1003

  Fly   903 IRESVAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNL 967
            |.:.|.::.....:.:.......:.||.|:||.|.|.|.:.:|..|..|.|..|...:|:.|.::
  Rat  1004 IVDHVDWMTSPEQVADSVKRFRDALWPNGILAEAAPCRDKAIRMRTRIAGKTKLFAVMPDELKHI 1068

  Fly   968 VGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIR 1010
            :||:..::|:|:||:..|:...|:::.|..||..:...||:.:
  Rat  1069 IGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYK 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	55/179 (31%)
		RGS_SNX25	422..531	CDD:188675	33/136 (24%)
		PX_SNX25	645..788	CDD:132788	30/173 (17%)
		Nexin_C	882..987	CDD:462541	35/108 (32%)
Snx13	XP_006240084.1	PHA03307	<2..>145	CDD:223039
		PXA	273..460	CDD:470618	60/221 (27%)
		RGS_SNX13	553..687	CDD:188674	33/136 (24%)
		PX_SNX13	733..863	CDD:132783	32/182 (18%)
		Nexin_C	979..1087	CDD:462541	34/107 (32%)