Protein Alignment snz and Snx14

DIOPT Version :9

• Sequence 1: NP_001284993.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_038937462.1
• Gene: Snx14 / 315871
• RGDID: 1310921
• Length: 984
• Species: Rattus norvegicus
• Alignment Length: 1137
• Identity: 227/1137 - (19%)
• Similarity: 398/1137 - (35%)
• Gaps: 363/1137 - (31%)

  Fly    14 RRLPLFPIEPEPSVTATQRLTLLATRLLRALQLNWRIIVSGITL-------TLLAVIWYYPTFFL 71
            |:.|||..    .:......:||..|.|..|.:.|..:...:|.       :||      |..|.
  Rat    53 RQYPLFCF----LLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLL------PNIFF 107

  Fly    72 FFAFVVYSLVL--VF-----AAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNATKSNIFDLPKPIK 129
            ...:....|.|  :|     .||.|.|..           ....||.||.|.         :|.
  Rat   108 TIKYKPKQLGLQELFPQGHSCAVCGKVKC-----------KRHRPSLLLENY---------QPW- 151

  Fly   130 NPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDV---VREDLWNAIQKIHERA 191
                |.|.....||..|.:::|.||.:|:.||...|......::::   :|......:::||
  Rat   152 ----LDLKVSSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIH--- 209

  Fly   192 LRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVFSTNSY-------LADEEKEMEFLRK 249
             ::|...||...::.....|:|.|..|..:...|......:...|       |.....|:::|||
  Rat   210 -KVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPDLHVALRSRRDELQYLRK 273

  Fly   250 LCEIMVILLLPRGYSLPP-------LKVLLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLA 307
            |.|    ||.|  |.|||       |.:|:.||||..:|.|.:..|..||.:|..::..|:.
  Rat   274 LTE----LLFP--YILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDD--- 329

  Fly   308 AAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHS 372
              :..:::.|.|:....||:                                  |..:|.::..|
  Rat   330 --SPPEKATEPASPLVPFLQ----------------------------------KFAEPRNKKPS 358

  Fly   373 LSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLE 437
            :.|.||       :.:|:                     ..|:   |...:|          ||:
  Rat   359 VLKLEL-------KQIRE---------------------QQDL---LFRFMN----------FLK 382

  Fly   438 PLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDK----HE--RKLIETFLL 496
            ...|..::.|.|.|||...                  |:.:.|:..|:    ||  :|:.:|:.|
  Rat   383 QEGAVHVLQFCLTVEEFND------------------RILRPELSNDEMLSLHEELQKIYKTYCL 429

  Fly   497 GDA------EPDIFYDIQR-----------------------NVLRTLEEKYYPPFVLSDQY-RQ 531
            .::      :|.|..:|||                       :||..||..:.|.|..||:| ||
  Rat   430 DESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQ 494

  Fly   532 LKEALDSNEIADPTLLMCHTIGDVQEPLAD----EQPGAADGLNGGAGGAIDVAAHTSYARRKLE 592
            |....:|     ||.......|.:.  |.|    ::.|.:.|::
  Rat   495 LLRGAES-----PTRNSKFNRGSLS--LDDFRSTQKRGESFGIS--------------------- 531

  Fly   593 QIQERIDKKNQALDALKYSVKPESKVLT---ILEKEMEWLK------SEKRQTEAHLRRTDAWTE 648
                ||..|   :..:..|...|..||.   :.|.|.::::      .:....||  ..|.....
  Rat   532 ----RIGSK---IKGVFKSTTMEGAVLPSYGVAEGEDDFIEEGIVVLEDDSPVEA--VSTPNTPR 587

  Fly   649 HLGKWKATIQSVEV-----SDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGIS 708
            :|..||.:|..|:.     |:.||..:.:.:..:|.:                 .|.|:......
  Rat   588 NLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVE-----------------RNDRRAVGHEP 635

  Fly   709 SGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPT-------NFKFFFLKTDRHGQEKAKSQIQKFL 766
            ..|.|.|...:.:.|:.||...........||:       |::  |||:.|       .:.|::|
  Rat   636 EHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYE--FLKSKR-------EEFQEYL 691

  Fly   767 NFILEDDHLNGSEAIYTFLSPS---SDHLKQSLPSPKKSKFSLSTLFRSDAGK-AHEASKATDPF 827
            ..:::...|:.|:.:..||||:   :..|.:.||.     .:|..:.:|..|| ..|..:..:||
  Rat   692 QKLVQHPELSNSQLLADFLSPNGGETQFLDKILPD-----VNLGKIIKSVPGKLMKEKGQHLEPF 751

  Fly   828 WGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYALMGEIF------------------ 874
                     |.::::.....:.|....:|......:|....|..::|
  Rat   752 ---------IMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNY 807

  Fly   875 -----DMGGVF--------------KWLRKSLISFVQITYGRTI----NRQIRESVAYLFEESML 916
                 .:.||:              .||...|:. .:|.:..|:    :..::..:..||:|..|
  Rat   808 FMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMG-TRILFKNTLEMYTDYYLQCKLEQLFQEHRL 871

  Fly   917 HNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVF 981
            .:..:.:..:.:    ..:..|...:|.::......:.:: ::||:::...:|.:.....:..:|
  Rat   872 VSLITLLRDAIF----CENTEPRSLQDKQKGAKQTFEEMM-NYIPDLIVKCIGEETKYESIRLLF 931

  Fly   982 DALQNPAYNKQLFYELLEILMIEFFPEIRQLR 1013
            |.||.|..||||.|.||:|::.|.|||:.:::
  Rat   932 DGLQQPVLNKQLTYVLLDIVIQELFPELNKMQ 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373	48/173 (28%)
		RGS_SNX25	422..531	CDD:188675	31/144 (22%)
		PX_SNX25	645..788	CDD:132788	31/154 (20%)
		Nexin_C	882..987	CDD:285792	18/108 (17%)
Snx14	XP_038937462.1	PXA	157..326	CDD:396666	48/178 (27%)
		RGS_SNX14	367..493	CDD:188677	34/177 (19%)
		PX_SNX14	591..713	CDD:132787	30/147 (20%)
		Nexin_C	834..938	CDD:400794	18/109 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810