DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snz and SNX24

DIOPT Version :9

Sequence 1:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	XP_011541651.1	Gene:	SNX24 / 28966	HGNCID:	21533	Length:	246	Species:	Homo sapiens

Alignment Length:	122	Identity:	30/122 - (24%)
Similarity:	51/122 - (41%)	Gaps:	26/122 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 PKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVFST 233
            ||:: :..|:.|...:|.:   .|..:....:.:|.:|  ..||..:..||            |.
Human   101 PKVL-EQRRQGLETYLQAV---ILENEELPKLFLDFLN--VRHLPSLPKAE------------SC 147

  Fly   234 NSYLADEEKEMEFLRKLCEIMVILLLPRGYSLPPL----KVLLSEILSYKIFFPMIK 286
            .|:   :|.|.|...||....|:|.|...|.||..    .|::..:| :.||:|.::
Human   148 GSF---DETESEESSKLSHQPVLLFLRDPYVLPAASDFPNVVIEGVL-HGIFYPHLQ 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373	30/122 (25%)
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:285792
SNX24	XP_011541651.1	PX_SNX22	1..144	CDD:132790	10/48 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900