Protein Alignment snz and SGK3

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_037389.4
• Gene: SGK3 / 23678
• HGNCID: 10812
• Length: 496
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 61/263 - (23%)
• Similarity: 93/263 - (35%)
• Gaps: 90/263 - (34%)

  Fly   128 IKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERAL 192
            :||..: |.:.|.....|..:.:.:|| ||        |...:|...:.||      :...|...
Human   215 LKNVKH-PFLVGLHYSFQTTEKLYFVL-DF--------VNGGELFFHLQRE------RSFPEHRA 263

  Fly   193 RMDAAKI---------------------IAVDMVNRVTVHLEKIRIAEARAAETNTPPVF-STNS 235
            |..||:|                     |.:|.|..|.  |....:.:...|.::|...| .|..
Human   264 RFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVV--LTDFGLCKEGIAISDTTTTFCGTPE 326

  Fly   236 YLADEEKEMEFLRK-----------LCEIMVILLLPRGYSLPPLKV---------LLSEILSYKI 280
            |||.     |.:||           |..::..:|    |.|||...         :|.:.||.:
Human   327 YLAP-----EVIRKQPYDNTVDWWCLGAVLYEML----YGLPPFYCRDVAEMYDNILHKPLSLR- 381

  Fly   281 FFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELS---LIR 342
              |.:. |||...:.:.:.::.:.||.|.             ||||: |.|....|.||   |::
Human   382 --PGVS-LTAWSILEELLEKDRQNRLGAK-------------EDFLE-IQNHPFFESLSWADLVQ 429

  Fly   343 KSI 345
            |.|
Human   430 KKI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	42/199 (21%)
		RGS_SNX25	422..531	CDD:188675
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:462541
SGK3	NP_037389.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PX_CISK	12..120	CDD:132780
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..156
		STKc_SGK3	165..490	CDD:270755	61/263 (23%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205