Protein Alignment snz and Pxk

DIOPT Version :9

• Sequence 1: NP_001284993.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_663433.2
• Gene: Pxk / 218699
• MGIID: 1289230
• Length: 582
• Species: Mus musculus
• Alignment Length: 660
• Identity: 120/660 - (18%)
• Similarity: 214/660 - (32%)
• Gaps: 248/660 - (37%)

  Fly   134 LPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAK 198
            :||.........||...||::|               :...:..|:.|..:::..:..|..::.:
Mouse    18 VPLTAAVEASQSLQSHTEYIIR---------------VQRGISAENSWQIVRRYSDFDLLNNSLQ 67

  Fly   199 IIAVDM---VNRVTVHLEKIRIAEARAAETNTPPVFSTNSYLADEEKEMEFLRKLCEIMVILLLP 260
            |..:.:   ..::..::::..|||.:....|...|...|..|::           ||::...|.|
Mouse    68 ITGLSLPLPPKKLIGNMDREFIAERQRGLQNYLNVIMANHVLSN-----------CELLKKFLDP 121

  Fly   261 RGYSLPPLKVLLSEILSY----------------------KIFFPMIK-------MLT----APD 292
            ..||....::.|.::..:                      |.|...||       :|:    .||
Mouse   122 NNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPD 186

  Fly   293 -YINQKVVQNIETRLAAAAMSKRSYEYAASFED-------FLKIINNSGNLEELSLIRKSIVNDL 349
             |::.|..|.:...|.:..   ..|.|..:|..       .::..|..|.|::|
Mouse   187 KYLSDKDFQCLIKLLPSCV---HPYIYRVTFATASESSALLIRAFNEKGTLKDL----------- 237

  Fly   350 MHATTMQNLQRAKGLDPDHEDH-SLSKSELTAAVRLKRYVRQLTMA------KGECEKNLAKFGW 407
                    :.:||..||..:.: :..|::.....::|.|.||:..|      ||        |.:
Mouse   238 --------IYKAKPKDPFLKKYCNPKKTQGLELQQIKTYGRQILEALKFLHDKG--------FPY 286

  Fly   408 NGNYSSDIDL-----TLVEILNTAVG-----RRYFTLFLEPLKASALIGFYLAVEEIKHAHKSAS 462
            ...:::::.|     .|:::.|:.:|     |.|||.|                .:|........
Mouse   287 GHLHAANVMLDGNTCRLLDLENSLLGLPSFYRSYFTQF----------------RKINTLESVDV 335

  Fly   463 HQLGTEIF-YTYIRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYPPFVLS 526
            |..|..:: .||.|.|.| :.:|.                                  :||....
Mouse   336 HCFGHLLYEMTYGRPPDS-VPVDS----------------------------------FPPASSL 365

  Fly   527 DQYRQLKEALDSNEIAD--PTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARR 589
            .....|:..|......:  ||:...     :|.||..                 ||...||
Mouse   366 AVVAVLESTLSCEACKNGMPTVSRL-----LQMPLFS-----------------DVLLTTS---- 404

  Fly   590 KLEQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEH----- 649
              |:.|.:|..|.:  :||:.:.:...|.||          .|::|...|.|.|.|.:.|
Mouse   405 --EKPQFKIPTKLK--EALRIAKECIEKRLT----------EEQKQIHQHRRLTRAQSHHGSEEE 455

  Fly   650 ------LGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKN-GDSGHANLRKRPS-- 705
                  |.:.|:...:||.|:|:                 ||:.::|.| ..||.::....||
Mouse   456 RKRRKILARKKSKRSAVENSEEQ-----------------PVKHSNSNNSAGSGASSPLTSPSSP 503

  Fly   706 ------GISS 709
                  |:||
Mouse   504 TPPSTAGLSS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373	32/193 (17%)
		RGS_SNX25	422..531	CDD:188675	18/114 (16%)
		PX_SNX25	645..788	CDD:132788	19/85 (22%)
		Nexin_C	882..987	CDD:285792
Pxk	NP_663433.2	PX_MONaKA	13..132	CDD:132781	24/139 (17%)
		PKc	198..345	CDD:270622	33/192 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..550		24/98 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900