DRSC/TRiP Functional Genomics Resources

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Protein Alignment snz and Sgk3

DIOPT Version :9

Sequence 1:NP_001284993.1 Gene:snz / 31704 FlyBaseID:FBgn0029976 Length:1117 Species:Drosophila melanogaster
Sequence 2:NP_001032848.1 Gene:Sgk3 / 170755 MGIID:2182368 Length:496 Species:Mus musculus


Alignment Length:365 Identity:73/365 - (20%)
Similarity:126/365 - (34%) Gaps:108/365 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   275 ILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSK----RSYEYAASFEDFLKIINNSGNL 335
            |:.||...|.:.:.::.::..:|....:...|.:...|:    |.|   |.|:.....:......
Mouse     6 IMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRY---AEFDKLYNSLKKQFPA 67

  Fly   336 EELSLIRKSIVNDLMHATTMQNLQRAKGLD---------PDHEDHSLSKSELTAAVRLKRYVRQL 391
            ..|.:..|.|..|......::  ||..||:         |:..:|    .::.|.:::.....|.
Mouse    68 MALKIPAKRIFGDNFDPDFIK--QRRAGLNEFIQNLVRYPELYNH----PDVRAFLQMDSPRHQS 126

  Fly   392 TMAKGECEKNLAK---------FGWNGN-YSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIG 446
            ..::.|.|::.:|         .|..|| ::...|...:::    :|:..|...|  |....|.|
Mouse   127 DPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKV----IGKGSFGKVL--LAKRKLDG 185

  Fly   447 FYLAV-----------EEIKHAH-------KSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIET 493
            .:.||           :|.||..       |:..|.....:.|::....|....:|         
Mouse   186 KFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLD--------- 241

  Fly   494 FLLGDAEPDIFYDIQRNVLRTLEE---KYYPPFVLSD---------QYRQLKE---ALDSN---- 539
            |:.|.   ::|:.:||.  |:..|   ::|...:.|.         .||.||.   .|||.    
Mouse   242 FVNGG---ELFFHLQRE--RSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVV 301

  Fly   540 -----------EIADPTLLMCHTIGDVQEPLADE----QP 564
                       .|:|.|...|.|    .|.||.|    ||
Mouse   302 LTDFGLCKEGIAISDTTTTFCGT----PEYLAPEVIRKQP 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snzNP_001284993.1 PXA 142..299 CDD:280373 5/23 (22%)
RGS_SNX25 422..531 CDD:188675 26/138 (19%)
PX_SNX25 645..788 CDD:132788
Nexin_C 882..987 CDD:285792
Sgk3NP_001032848.1 PX_CISK 12..120 CDD:132780 19/116 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..157 7/35 (20%)
S_TKc 162..419 CDD:214567 43/200 (22%)
STKc_SGK3 165..490 CDD:270755 43/197 (22%)
Nuclear localization signal. /evidence=ECO:0000250 195..205 1/9 (11%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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