Protein Alignment snz and Kif16b

DIOPT Version :9

• Sequence 1: NP_001284993.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_036014693.1
• Gene: Kif16b / 16558
• MGIID: 1098240
• Length: 1908
• Species: Mus musculus
• Alignment Length: 1181
• Identity: 213/1181 - (18%)
• Similarity: 369/1181 - (31%)
• Gaps: 482/1181 - (40%)

  Fly   112 LLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVV 176
            :|||   ..:|    |||.|..|.|.|.:....:|:::                .:|.|||.::.
Mouse   624 MLYN---PGLF----PIKGPICLRLEFERQQREELEKL----------------ESKRKLIEEME 665

  Fly   177 R---------EDLWNAIQ------KIHERALRMDAAKIIAVDMVNRVTVHL---------EKIRI 217
            .         |.:...::      :|.:|.:|...      :.:.|.:.|:         ||.|.
Mouse   666 EKQKSDKAELERMQQEVETRRKETEIVQRQIRKQE------ESLKRRSFHIENKLKDLLAEKERF 724

  Fly   218 AEARAAETNTPPVFSTNSYLADEEKEM----EFLRKLCEIMVILLLPRGYSLPPLKVLLSEILSY 278
            .|.|..|..     ........||:.:    |.||||.|                  |.|...:.
Mouse   725 EEERLREQQ-----GLEQQRRQEEESLFRIREELRKLQE------------------LNSHEQAE 766

  Fly   279 KIFFPMIKMLTAPDYINQKV-VQNIETRLAAAAM---SKRSYEYAASFEDFLKIINNSGNL---- 335
            |     :::....|.::|:. .|:.:.||....:   .|...:..|..|:.|:...::..|
Mouse   767 K-----VQIFQELDRLHQEQNAQSAKLRLEKRRLEEEEKEQVQRVAHLEEQLRKRQDTAPLLCPG 826

  Fly   336 ---------EELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAA----VRLKRY 387
                     .||..||::    |:.|..|    ||.|      ||: .:.||..|    :..||
Mouse   827 EAQRAQEEKRELESIREA----LLQAKEM----RAGG------DHT-CRDELERAQQYFLEFKR- 875

  Fly   388 VRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIG---FYL 449
             ||| :.....||:|.:         ..||...|:....|.       ||.:|..|  |   .:|
Mouse   876 -RQL-VKLASLEKDLVQ---------QKDLLSKEVQEEKVA-------LEHVKCDA--GGDPSFL 920

  Fly   450 AVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRT 514
            |.::        .:.||.......|:..::.:|..:|:                ..|:.:|.|
Mouse   921 ATDD--------GNILGGPPDLDKIKTAETRLQSREHQ----------------LQDLLQNHL-- 959

  Fly   515 LEEKYYPPFVLSDQYRQLKEALDSNEIA-DPTLLMCHT---IGDVQEPLADEQPGAA--DGLNGG 573
                   |.:|.::.|.| :||||..:. |.||  |..   :|:.:|.:|..|..|:  ..|...
Mouse   960 -------PALLEEKQRVL-DALDSGVLGLDTTL--CQVEKEVGEKEEQIAQYQANASQLQQLRAT 1014

  Fly   574 AGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSV-KPESKVLTI-----LEKEMEWLKSE 632
            .....:||......|||.::|.|..:|  |..:||:.:| |.|.:...:     |:.|::    |
Mouse  1015 FEFTANVARQEEKVRRKEKEILESQEK--QQREALEQAVAKLEQRRSALQRCSTLDLEIQ----E 1073

  Fly   633 KRQTEAHLRRTDAWTEHLGKWKATIQS-------------VEVSDEKES---------------- 668
            :||....| .|..|:    .|:|::::             .|:...|:.
Mouse  1074 QRQKLGSL-HTSEWS----GWQASLETDGEALEMDPARLEHEIHQLKQKICEVDGVQRPHHGILE 1133

  Fly   669 --------------------LQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVV 713
                                :...|..:::|::...:.......||:.|.     |:.      |
Mouse  1134 GQAVLSSLPPSGGNSHLAPLMDARISAYIEEEVQRRLHDLHRAIGDANHT-----PAD------V 1187

  Fly   714 MRSLNQVHE--LQRKLRHVSS------------NLKAIDLPTNFK-------------------- 744
            |:|..::|.  .||||::.:.            :..|.|.|:..:
Mouse  1188 MKSNEELHNGTTQRKLKYETGQPWSAPCVIPLLSKDAADSPSVLREESEMCPSSQRSHLMSQNTS 1252

  Fly   745 ----FFFLKTDR----HGQEKAKSQIQKFL------------NFILEDDHLN------------- 776
                |.....:|    .|.|..|:...||.            ..:||...||
Mouse  1253 LSTAFSMASQERMVLHSGTELLKNIGDKFCYPENSGHLEPNRAHLLEITSLNERSSRDAQNSQGE 1317

  Fly   777 ----------------GSEAIYTFLSPSSDHLKQSLPSPKKS---------KFSLS-TLFRSDAG 815
                            |.|:.:|.|    .|:.|.:|:.:.|         :|.|| :|.:.:..
Mouse  1318 SENGNGFMAPEEKQSWGIESSWTLL----QHVSQQVPANRGSQQAMQSRVLRFVLSESLSQREQP 1378

  Fly   816 KAHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKD-SIAEPMYALMGEIFDMGGV 879
            ......:.:.|....::.:|..|                  |:|: ||..|:.
Mouse  1379 TGSSPQRVSAPTLSCEQQNEKYS------------------DAKNTSILAPLV------------ 1413

  Fly   880 FKWLRKSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSEDM 944
                              .|..:.::.:.:.:.:      ||.:.|.  ..|.|..|........
Mouse  1414 ------------------NIRTEAKKQLGFFYHK------FSDLYKD--TSGHLIQAGTKVMSQA 1452

  Fly   945 REMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEI 1009
            :.:.:......||.|:...:          ||                       :.::|..|:.
Mouse  1453 KHVGSMCDPGELTSHVTTFI----------RG-----------------------LPLLEHLPQH 1484

  Fly  1010 RQLRVSNSNGTKLNTATAGAAAASAAAALVAATASASLP-----SLNHSGGG---HSASTGGHQN 1066
            ..||                       :|:..:....||     |.|..|||   .:.||..|:|
Mouse  1485 LPLR-----------------------SLMVPSGPPPLPETQIGSFNSEGGGSPRSAKSTAPHRN 1526

  Fly  1067 HQGSSSASGSS 1077
            ...:|:.:.:|
Mouse  1527 LAFTSTDAPNS 1537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_001284993.1	PXA	142..299	CDD:280373	30/185 (16%)
		RGS_SNX25	422..531	CDD:188675	18/111 (16%)
		PX_SNX25	645..788	CDD:132788	37/274 (14%)
		Nexin_C	882..987	CDD:285792	12/104 (12%)
Kif16b	XP_036014693.1	KISc_KIF1A_KIF1B	51..399	CDD:276816
		Kinesin_assoc	398..510	CDD:406567
		FHA	512..577	CDD:395400
		SbcC	<644..1081	CDD:223496	117/564 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900