Protein Alignment snz and SNX20

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_878274.1
• Gene: SNX20 / 124460
• HGNCID: 30390
• Length: 316
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 69/333 - (20%)
• Similarity: 118/333 - (35%)
• Gaps: 98/333 - (29%)

  Fly   354 TMQNLQRAKGLDPD--------HED-HS-LSKSELTAAVRLKRY-------------VRQLTMAK 395
            |.:..|.|....||        |.| || ||.:.......|::|             :.::..|:
Human    20 TARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTRELQQYWQNQKCRWKHVKLLFEIASAR 84

  Fly   396 GECEKNLAKFG-------WNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEE 453
            .| |:.::||.       ..|::.:          |.||..|.::.|.: |:.:.|..|...:|:
Human    85 IE-ERKVSKFVVYQIIVIQTGSFDN----------NKAVLERRYSDFAK-LQKALLKTFREEIED 137

  Fly   454 IKHAHKSASHQLGTEIFYTYIRVPKS------EIQIDKHERKLIETFLLGDAEPDIFYDIQRNVL 512
            ::...|..:.....|:.....|..:.      .|:..:..|:.:: ||   ..|::     |...
Human   138 VEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLD-FL---TRPEL-----REAF 193

  Fly   513 RTLEEKYYP-PFVLSDQYRQLKEALDSN--EIADPTL---LMCHTIGDVQEPLADEQPGAADGLN 571
            ..|....|| ...|..:...|:|.|.::  ..|.|.|   |:||.  |:..|        |:...
Human   194 GCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHR--DLDRP--------AEAFA 248

  Fly   572 GGAGGAIDVAAHTSYARRKLEQIQERIDKKNQA--LDALKYSVKPESKVLTILEKEMEWLKSEKR 634
            .|              .|.|:::|.|...:..|  |||:........|....|::.:|
Human   249 AG--------------ERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLE------- 292

  Fly   635 QTEAHLRR 642
              |:.|||
Human   293 --ESQLRR 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484
		RGS_SNX25	422..531	CDD:188675	22/115 (19%)
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:462541
SNX20	NP_878274.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..54		10/30 (33%)
		PX_SNX20	76..189	CDD:132833	23/128 (18%)