DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment snz and Snx21

DIOPT Version :9

Sequence 1:NP_001284993.1 Gene:snz / 31704 FlyBaseID:FBgn0029976 Length:1117 Species:Drosophila melanogaster
Sequence 2:XP_030102304.1 Gene:Snx21 / 101113 MGIID:1917729 Length:372 Species:Mus musculus


Alignment Length:346 Identity:68/346 - (19%)
Similarity:111/346 - (32%) Gaps:98/346 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   678 DEDINAPVQPTSSKNGDSGH-ANLRKRPSGISSGWVVMRSLNQVHEL-------QRKLRHVSSNL 734
            |||..|.:....|.:|.||. |.....|.|..|..::.|.|....:.       ||.|..|:|..
Mouse    65 DEDDEAGLDSPPSGDGASGEDAERSPPPDGQRSSQLLARQLQDFWKKSRNTLVPQRLLFEVTSAN 129

  Fly   735 KAIDLPTNFKFFFLKTDRH----------GQEKAKSQI-QKFLNFILEDDHLNGSEAIYTFLSPS 788
            ...|.|:.:..:.:..:..          ..::..:|| :::.:|  |..|.|...   .|..|.
Mouse   130 VVKDPPSKYVAWVISEEPQLYTLAVMGPGPPDRQPAQISRRYSDF--ERLHRNLQR---QFRGPM 189

  Fly   789 SDHLKQSLPSPKK---SKFSLSTLFRSDAGKAHEASKATDPFWG--------------------- 829
            |     ::..|:|   ..|:..|:.|        .|:|.:.|.|                     
Mouse   190 S-----AISFPRKRLRRNFTAETIAR--------RSRAFEQFLGHLQAVPELRQAPDLQDFFVLP 241

  Fly   830 -LQRDDEDISTYLDGES---GGEAKMLAADLDSKDSIAEPMYALMG------EIFDMGGVFKWLR 884
             |:|......|.|..|:   ...|..|...|.:......|:..|.|      |:.|.|..     
Mouse   242 ELRRAQSLTCTGLYREALALWANAWQLQTQLGTPSGPDRPLLTLAGLAVCHQELEDPGEA----- 301

  Fly   885 KSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFSAILKSF----WPGGVLASAYPTRSEDMR 945
                            |...|....|..:...|.:.:..|::.    |..|:.......:.:.::
Mouse   302 ----------------RACSEKALQLLGDKRPHPFLAPFLEAHVRLSWRLGLDKRQSEAQLQALQ 350

  Fly   946 E--MTTTAAKALLTDHIPEVL 964
            |  :|:|...:|....|.|||
Mouse   351 EAGLTSTPPPSLKELLIKEVL 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snzNP_001284993.1 PXA 142..299 CDD:280373
RGS_SNX25 422..531 CDD:188675
PX_SNX25 645..788 CDD:132788 28/128 (22%)
Nexin_C 882..987 CDD:285792 15/89 (17%)
Snx21XP_030102304.1 PX_domain 121..241 CDD:383026 23/137 (17%)
TPR_12 243..312 CDD:315987 16/89 (18%)
TPR repeat 243..267 CDD:276809 6/23 (26%)
TPR repeat 280..311 CDD:276809 8/51 (16%)
TPR repeat 325..352 CDD:276809 3/26 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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