Protein Alignment spidey and IFA38

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_009717.1
• Gene: IFA38 / 852456
• SGDID: S000000363
• Length: 347
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 100/297 - (33%)
• Similarity: 169/297 - (56%)
• Gaps: 33/297 - (11%)

  Fly    49 SKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTG 113
            :|.|::..:||::|||||.:|:::|:||..||||||:..||..:.||:.|::.|.|:::.:|...
Yeast    59 AKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAE 123

  Fly   114 GDEI-YDKIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFL 177
            ..|. |:.|:|....|.:.|||||||.|:..|..||:..:.:   ||||:..|..:...:|.:..
Yeast   124 DKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKE---LRNIITINNTATLLITQIIA 185

  Fly   178 PGMI---------SQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQS 233
            |.::         |..||:|:.:.|..|:||.|||:.||.:|:|:..:|:.|..|..:..|.::.
Yeast   186 PKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVEL 250

  Fly   234 VQPGFVATNMSKIRKASVFAPSPETYVRSALSTLG--------IATQTAGYLPHALLQLVIHFTE 290
            :....|.::|||||::|:..|:|:.:|:|.|.::|        .||.|. |..||:.|.||..|.
Yeast   251 IISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTP-YWAHAVYQFVITETF 314

  Fly   291 AVFGE-------QFARNIVMKNILGTRKRALRRLAKE 320
            .|:.:       .|.::|.::.:    |:|.|::.||
Yeast   315 GVYSKIVNSINYSFHKSIRIRAL----KKAARQVKKE 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	90/253 (36%)
IFA38	NP_009717.1	17beta-HSD1_like_SDR_c	62..310	CDD:187614	88/251 (35%)