DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spidey and KCR1

DIOPT Version :9

Sequence 1:	NP_572420.1	Gene:	spidey / 31703	FlyBaseID:	FBgn0029975	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_564905.1	Gene:	KCR1 / 843098	AraportID:	AT1G67730	Length:	318	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	123/320 - (38%)
Similarity:	191/320 - (59%)	Gaps:	24/320 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLSLLGGLAIGIVGFQVFRKVLPWIYANVVGPKVFGSSVDLSKMGEWAVVTGSTDGIGKAYAKEL 72
            :|.:||.::|    |:....:|...|...:.|     |.:|.:.|.||::||.|||||||:|.:|
plant    16 ILFVLGSISI----FKFIFTLLRSFYIYFLRP-----SKNLRRYGSWAIITGPTDGIGKAFAFQL 71

  Fly    73 ARRGLKLVLISRSLEKLNVVAKEIGDKYG-VEVRVIDVDFTGG-DEIYDKIREKTTGLNVGVLVN 135
            |::||.|:|::|:.:||..|:..|..||. .::..:.:||:|. ||...:|:|...||:||:|:|
plant    72 AQKGLNLILVARNPDKLKDVSDSIRSKYSQTQILTVVMDFSGDIDEGVKRIKESIEGLDVGILIN 136

  Fly   136 NVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINV-SSTAGVIP 199
            |.|:||.:.:||   ::.|...:.|::..|:...|.:|...||.|:.:::|.|||: |..|.:||
plant   137 NAGMSYPYAKYF---HEVDEELINNLIKINVEGTTKVTQAVLPNMLKRKKGAIINMGSGAAALIP 198

  Fly   200 N-PLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYVRSA 263
            : |..|||:..|.:|::|:..|..|||:.||.:|...|.:|||.|:|||:||....|||.|.::|
plant   199 SYPFYSVYAGAKTYVDQFTKCLHVEYKKSGIDVQCQVPLYVATKMTKIRRASFLVASPEGYAKAA 263

  Fly   264 LSTLGIATQTAGYLPHALLQLVIH-FTEAVFGEQFARNIVMKNILGTRKRALRR--LAKE 320
            |..:|...|...|.||||:..|:. ..|:|| |.|  ||  |..|..||:.|::  :.||
plant   264 LRFVGYEAQCTPYWPHALMGAVVSALPESVF-ESF--NI--KRCLQIRKKGLQKDSMKKE 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	PLN02780	8..321	CDD:166421	123/320 (38%)
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	99/240 (41%)
KCR1	NP_564905.1	PLN02780	1..318	CDD:166421	121/318 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	153	1.000	Domainoid score	I1365
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H95094
Inparanoid	1	1.050	196	1.000	Inparanoid score	I1339
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D895581at2759
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	1	1.000	-	-		mtm1136
orthoMCL	1	0.900	-	-		OOG6_100431
Panther	1	1.100	-	-	LDO	PTHR43899
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X484
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840