Protein Alignment spidey and Hsd17b2

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_077367.2
• Gene: Hsd17b2 / 79243
• RGDID: 621803
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 207
• Identity: 59/207 - (28%)
• Similarity: 105/207 - (50%)
• Gaps: 11/207 - (5%)

  Fly    41 VFGSSVDLSKMGEWAV-VTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEV 104
            |..|..||..:.:.|| |||:..|.|.|.||.|.:.|  ..:.:..|:|....|:|:.......:
  Rat    71 VSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLG--FTVFAGVLDKEGPGAEELRKNCSERL 133

  Fly   105 RVIDVDFTGGDEIYD---KIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANI 166
            .|:.:|.|..::|.|   ::.||.....:..:|||.|:.:    :.:|.........|..:|.|.
  Rat   134 SVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLH----FPIDGELIPMTVYRKCMAVNF 194

  Fly   167 HSVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILI 231
            .....:|.:||| ::.:.:|.::||||...:||..:::.|:||||.::.||..::.|..:.|:.:
  Rat   195 FGAVEVTKVFLP-LLRKSKGRLVNVSSMGAMIPFQMMAAYASTKAAISMFSAVIRQELAKWGVKV 258

  Fly   232 QSVQPGFVATNM 243
            .::.||...||:
  Rat   259 VTIHPGGFQTNI 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	55/196 (28%)
Hsd17b2	NP_077367.2	type2_17beta_HSD-like_SDR_c	84..364	CDD:187665	55/194 (28%)