Protein Alignment spidey and Hsdl1

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_780394.1
• Gene: Hsdl1 / 72552
• MGIID: 1919802
• Length: 330
• Species: Mus musculus
• Alignment Length: 280
• Identity: 115/280 - (41%)
• Similarity: 166/280 - (59%)
• Gaps: 18/280 - (6%)

  Fly    43 GSSVDLSKM-GEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRV 106
            ||..||.|. |.|||::|:|||||||||:|||..||.::|||:..|||...||.|.|.|.||..|
Mouse    57 GSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLV 121

  Fly   107 IDVDFTGGDEIYDKIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTH 171
            :..||:.|.|||..|||.....::|:|||:||..|.:|:||   .:.....|.:||..||.:.:.
Mouse   122 LVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYF---SQVPEDTLWDIVNVNIAAASL 183

  Fly   172 MTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQP 236
            |..:.||||:.:::|.|:.|||.:...|.|.|:.:|::||:::.||..||.||...||.:||:.|
Mouse   184 MVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIP 248

  Fly   237 GFV----ATNMSKIRKASVFAPSPETYVRSALSTLGIATQTAGYLPHALLQLVIHFTEA---VFG 294
            .:|    |...|.:.:....||||..|.:.|:|||||:.:|.||..|::..|...:...   |:|
Mouse   249 FYVTSSGAAPASFLHRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWG 313

  Fly   295 EQFARNIVMKNILGTRKRAL 314
                .|::.:::   ||.||
Mouse   314 ----ANLLNRSL---RKEAL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	103/239 (43%)
Hsdl1	NP_780394.1	Required for mitochondria translocation. /evidence=ECO:0000250	2..82		15/24 (63%)
		17beta-HSD1_like_SDR_c	67..309	CDD:187614	103/244 (42%)