Protein Alignment spidey and hsd17b11

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001011304.1
• Gene: hsd17b11 / 496757
• XenbaseID: XB-GENE-1004190
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 268
• Identity: 75/268 - (27%)
• Similarity: 115/268 - (42%)
• Gaps: 34/268 - (12%)

  Fly    49 SKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKY---GVEVRVIDVD 110
            |..||..::||:..||||..|:....  |:.||:...:.|..|  :|..:|.   |.:|....||
 Frog    33 SVKGEVVLITGAGHGIGKITAQIFGE--LESVLVLWDINKQGV--EETAEKCRKGGAKVYTYVVD 93

  Fly   111 FTGGDEI---YDKIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHM 172
            .:..:||   .:|::::..  :|.:|:||.||.:......|...:.:..|..||:|   |..|
 Frog    94 CSKREEINTAANKVKQEVG--DVTILINNAGIIFCADVLTLQDQQIEKIFEVNILA---HFWT-- 151

  Fly   173 TALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTE---YKEHGILIQSV 234
            |..|||.|:....|.|:.|:|:||.:....:..|.|||.....:...|..|   ..:.||....:
 Frog   152 TRAFLPSMLRNNHGHIVTVASSAGFVGVQFMVDYCSTKFAALGYHKALTAELLALGKSGIKTSCL 216

  Fly   235 QPGFVATNMSK---IRKASVFAPS--PETYVRSAL---------STLGIATQTAGYLPHALLQLV 285
            .|.||.|...|   :|.|.|..|.  .:|.|...|         |::.:....|.:||...|..:
 Frog   217 CPVFVDTGFVKNPSLRLAPVLQPEEVAQTLVDGILINKKMICVPSSVSLVPVLAFFLPERALNAL 281

  Fly   286 IHFTEAVF 293
            ..|....|
 Frog   282 NEFQNLKF 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	72/258 (28%)
hsd17b11	NP_001011304.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	69/249 (28%)