Protein Alignment spidey and hsd17b3

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: XP_073765320.1
• Gene: hsd17b3 / 393335
• ZFINID: ZDB-GENE-040426-1339
• Length: 324
• Species: Danio rerio
• Alignment Length: 282
• Identity: 111/282 - (39%)
• Similarity: 169/282 - (59%)
• Gaps: 19/282 - (6%)

  Fly     8 VLSLLGGLAIGIVGFQVFRKVLPWI---YANVVGPKVFGSSVDLSKMGEWAVVTGSTDGIGKAYA 69
            :..|.|..||.:.|.::...::.:|   :..:  |:.|.:|     :|:|||:||.:||||:|||
Zfish     7 IFVLTGTCAILVFGGKIASLIMMFITKLFCPL--PEAFFTS-----LGKWAVITGGSDGIGRAYA 64

  Fly    70 KELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTGGDEIYDKIREKTTGLNVGVLV 134
            :||:::|:.:::|||:.|||:..||:|....|.:|:||..||| .|:||..|.|...||::||||
Zfish    65 EELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFT-KDDIYGHITENIEGLDIGVLV 128

  Fly   135 NNVGISYGHPEYFLDCYKADPPFLR----NIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTA 195
            |||||....    :.|...:...|.    :||..|:.|:..|..:.||||..:|||||:||||..
Zfish   129 NNVGILPSQ----IPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGI 189

  Fly   196 GVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYV 260
            ..||.|:.::|:::|.||.:||..||.||...|::||:|.|..|:|.|:..:|..:...:.|.:|
Zfish   190 AKIPCPIYTLYAASKVFVERFSQGLQAEYISKGVIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFV 254

  Fly   261 RSALSTLGIATQTAGYLPHALL 282
            ||:|..|....||.|.:.|.||
Zfish   255 RSSLKYLKTGDQTYGSITHTLL 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	102/235 (43%)
hsd17b3	XP_073765320.1	None