DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spidey and CG13284

DIOPT Version :9

Sequence 1:	NP_572420.1	Gene:	spidey / 31703	FlyBaseID:	FBgn0029975	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001260523.1	Gene:	CG13284 / 35021	FlyBaseID:	FBgn0032614	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	124/318 - (38%)
Similarity:	190/318 - (59%)	Gaps:	16/318 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SQVLSLLGGLAIGIVGFQVFRKVLPWIYANV---VGPKVFGSSVDLSKMGEWAVVTGSTDGIGKA 67
            |..:.|:|.|.||:..:...:.::..|.|.:   ..|.:..:.||  |.|:||||||:||||||.
  Fly    23 SAAIYLVGLLTIGVFLYDNLKSLVSIIKAVLEPYFQPHLPRTLVD--KFGQWAVVTGATDGIGKE 85

  Fly    68 YAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTGGDEIYDKIREKTTGLNVGV 132
            ||:||||:|:.||||||:.|||..|..||..:|.|:.:.|..||..|.|:||:|.::..|::||:
  Fly    86 YARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGI 150

  Fly   133 LVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTAGV 197
            ||||||:.|.||| .||....|  .|.|::..|:.|||.:|...||.||.:|:|.|:|:.|::.:
  Fly   151 LVNNVGMMYEHPE-SLDLVSED--LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSEL 212

  Fly   198 IPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMS----KIRKASVFAPSPET 258
            .|.|.::||:::|.||..||..|:.|..||.|.:|.|.|.||.|.|:    ::.:..:|.|:..|
  Fly   213 QPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYT 277

  Fly   259 YVRSALSTLGIATQTAGYLPH----ALLQLVIHFTEAVFGEQFARNIVMKNILGTRKR 312
            :.|||:.|||..::|.|:..|    |:::|.........|.|..:.:.::.:...:|:
  Fly   278 FARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFKRLRIEALEQKQKK 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	PLN02780	8..321	CDD:166421	123/316 (39%)
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	109/243 (45%)
CG13284	NP_001260523.1	DltE	70..323	CDD:223377	111/255 (44%)
CG13284	NP_001260523.1	17beta-HSD1_like_SDR_c	70..309	CDD:187614	109/241 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447527
Domainoid	1	1.000	153	1.000	Domainoid score	I1365
eggNOG	1	0.900	-	-		E1_COG0300
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I1260
Isobase	1	0.950	-	0.803099	Normalized mean entropy	S1433
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D125652at50557
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	1	1.000	-	-		mtm1136
orthoMCL	1	0.900	-	-		OOG6_100431
Panther	1	1.100	-	-	P	PTHR43899
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	12	11.760