Protein Alignment spidey and hsd17b12a

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_957175.1
• Gene: hsd17b12a / 327417
• ZFINID: ZDB-GENE-030131-5628
• Length: 319
• Species: Danio rerio
• Alignment Length: 266
• Identity: 135/266 - (50%)
• Similarity: 182/266 - (68%)
• Gaps: 20/266 - (7%)

  Fly    19 IVGFQVFRKVLPWIYAN--VVGPKVFGSSVDLSKMGEWAVVTGSTDGIGKAYAKELARRGLKLVL 81
            |.||::      |:..|  ::.|          |:|:||||||:||||||:||:||||||..::|
Zfish    37 ITGFRI------WVLGNGDLLSP----------KLGKWAVVTGATDGIGKSYAEELARRGFSMML 85

  Fly    82 ISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTGGDEIYDKIREKTTGLNVGVLVNNVGISYGHPEY 146
            ||||.|||:.|||.:...|.||.:.|.|||:..| :|.||.:...||.:|:|||||||||.:||:
Zfish    86 ISRSQEKLDDVAKSLESTYKVETKTIAVDFSQID-VYPKIEKGLAGLEIGILVNNVGISYSYPEF 149

  Fly   147 FLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKA 211
            ||.....: .|:..::..||.||..||.|.||.|.::.:|||:|:||.:|:.|.|||::||||||
Zfish   150 FLHIPDLE-NFITTMINVNITSVCQMTRLVLPRMEARAKGVILNISSASGMFPVPLLTIYSSTKA 213

  Fly   212 FVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYVRSALSTLGIATQTAGY 276
            ||:.||..||||||..||:||||.|.||||.|:||||.::..|:||.||.:.|:|:|:..||.||
Zfish   214 FVDFFSRGLQTEYKCKGIIIQSVLPFFVATKMTKIRKPTLDKPTPERYVAAELNTVGLQDQTNGY 278

  Fly   277 LPHALL 282
            .|||::
Zfish   279 FPHAVM 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	128/231 (55%)
hsd17b12a	NP_957175.1	17beta-HSD1_like_SDR_c	56..288	CDD:187614	128/231 (55%)