Protein Alignment spidey and Ldsdh1

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 69/265 - (26%)
• Similarity: 115/265 - (43%)
• Gaps: 40/265 - (15%)

  Fly    52 GEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEI----GDKYGVEVRVIDVDFT 112
            |:..::||:..|:||..|.:.|:.|..::....:.:..|...|||    |..:|....|     |
  Fly    58 GKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKAFGYVCNV-----T 117

  Fly   113 GGDEIYD---KIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTA 174
            ..:|:.:   |:| |..|. :.|:|||.||...||  .|:..:.:   :|.:...|:.|...:..
  Fly   118 KREELIELAQKVR-KEHGF-IHVVVNNAGIMPCHP--LLEHTENE---IRLMYEINVLSHFWIIQ 175

  Fly   175 LFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFS----DDLQTEYKEHGILIQSVQ 235
            .|||.||.:..|.|:.:||.||:.....|..|..||..|..:.    ::|:.:..::.:.:.::.
  Fly   176 AFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQNNVKLTTIY 240

  Fly   236 PGFVAT-----------NMSKIRKASVFAPSPETYVRSALSTLGI-----ATQTAGYL-PHALLQ 283
            |..:.|           |:.|:..|.|.|.|.....|..|....|     |.:..|.| |...::
  Fly   241 PYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGLEEAAIPRHFVAAEKIGRLIPRKAMR 305

  Fly   284 LVIHF 288
            ||..|
  Fly   306 LVNDF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	68/263 (26%)
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	61/238 (26%)