DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spidey and stdh-2

DIOPT Version :9

Sequence 1:	NP_572420.1	Gene:	spidey / 31703	FlyBaseID:	FBgn0029975	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_507092.1	Gene:	stdh-2 / 184337	WormBaseID:	WBGene00008678	Length:	315	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	106/283 - (37%)
Similarity:	164/283 - (57%)	Gaps:	13/283 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLAIGIVGFQVFRKVLPWIYANVVGPKVFGSSVDLSKM--GEWAVVTGSTDGIGKAYAKELARRG 76
            |.|:.:..|..|.:::    .|::.|..|...:||.|.  ..||||||:||||||:|:.||||||
Worm    11 GAAVVLYIFYHFIRII----LNILVPYAFCQPIDLKKKAGASWAVVTGATDGIGKSYSFELARRG 71

  Fly    77 LKLVLISRSLEKLNVVAKEIGDKY-GVEVRVIDVDFTGGDEI-YDKIREKTTGLNVGVLVNNVGI 139
            ..:.::||:..||....|:|.:|. .:|||....|||..... |:|:..|...::||:|:||||:
Worm    72 FNVYIVSRTQSKLEQTKKDILEKQPDIEVRFATYDFTNPSVTDYEKLLSKLNEVSVGILINNVGM 136

  Fly   140 SYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLS 204
            .:.:|| .|.........:.|::..|....|.::|..||.|:|::.|:|:|:.|.|||:.....|
Worm   137 FFDYPE-MLHKINGGIDSIANVIIINTLPATLLSAGILPQMVSRKAGIIVNIGSFAGVVKLAEWS 200

  Fly   205 VYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYVRSALSTLGI 269
            :||:||.:|...:..|:.||..|||:.|::.|..|||.|:.....|.|.|..:|:.||||:|:|.
Worm   201 IYSATKKYVEWLTGCLRKEYSHHGIIFQAITPAMVATKMAGNPNTSFFCPDSDTFARSALNTIGH 265

  Fly   270 ATQTAGYLPH----ALLQLVIHF 288
            |::|.||:.|    .:|:|:..|
Worm   266 ASETTGYIAHQIQCEILKLLPDF 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	PLN02780	8..321	CDD:166421	106/283 (37%)
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	95/241 (39%)
stdh-2	NP_507092.1	PLN02780	19..312	CDD:166421	104/275 (38%)
stdh-2	NP_507092.1	17beta-HSD1_like_SDR_c	47..289	CDD:187614	96/243 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167862
Domainoid	1	1.000	148	1.000	Domainoid score	I2740
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H95094
Inparanoid	1	1.050	201	1.000	Inparanoid score	I2462
Isobase	1	0.950	-	0.803099	Normalized mean entropy	S1433
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	1	1.000	-	-		mtm4736
orthoMCL	1	0.900	-	-		OOG6_100431
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X484
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.620