Protein Alignment spidey and let-767

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001293606.1
• Gene: let-767 / 175895
• WormBaseID: WBGene00002891
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 319
• Identity: 123/319 - (38%)
• Similarity: 187/319 - (58%)
• Gaps: 24/319 - (7%)

  Fly    13 GGLAIGIVGFQVFRKVLPWIYANVVGPKVFGSSVDLSKM--GEWAVVTGSTDGIGKAYAKELARR 75
            |.:|:..|.:::..     |::|::||.|..|.:||.|.  ..||||||:|||||||||.|||||
 Worm    28 GYVALAAVAYRLLT-----IFSNILGPYVLLSPIDLKKRAGASWAVVTGATDGIGKAYAFELARR 87

  Fly    76 GLKLVLISRSLEKLNVVAKEIGDKY-GVEVRVIDVDFT-GGDEIYDKIREKTTGLNVGVLVNNVG 138
            |..::|:||:..||:...|||.:|| .:|||....||| .....|..:......:.:|||:||||
 Worm    88 GFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVG 152

  Fly   139 ISYGHPEYFLDCYKADPPF--LRNIVAANIHS----VTHMTALFLPGMISQRRGVIINVSSTAGV 197
            :||.:|:..   :|.|...  |.||...|...    :|.::|..||.|::::.|||:||.|:||.
 Worm   153 MSYEYPDVL---HKVDGGIERLANITTINTLPPTLFLTQLSAGILPQMVARKAGVIVNVGSSAGA 214

  Fly   198 IPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYVRS 262
            ....|.:|||:||.:|:..:..|:.||:..||.:|::.|..|||.|||:::.|.|.|....:.:|
 Worm   215 NQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKMSKVKRTSFFTPDGAVFAKS 279

  Fly   263 ALSTLGIATQTAGYLPHALLQLVIHFTEAVFGEQFARNIVMKNI-LGTRKRALRRLAKE 320
            ||:|:|..:.|.||:.|   ||.:...:.:  ..|.|:.::.|: :|||..|||:..:|
 Worm   280 ALNTVGNTSDTTGYITH---QLQLELMDLI--PTFIRDKILTNMSVGTRAAALRKKERE 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	101/243 (42%)
let-767	NP_001293606.1	17beta-HSD1_like_SDR_c	64..310	CDD:187614	101/253 (40%)