Protein Alignment spidey and Hsd17b2

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_032316.2
• Gene: Hsd17b2 / 15486
• MGIID: 1096386
• Length: 381
• Species: Mus musculus
• Alignment Length: 205
• Identity: 59/205 - (28%)
• Similarity: 102/205 - (49%)
• Gaps: 11/205 - (5%)

  Fly    44 SSVDLSKMGEWAV-VTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVI 107
            |..||..:.:.|| |||:..|.|...||.|.:.|  ..:.:..|:|....|:|:.......:.|:
Mouse    74 SDQDLLPVDQKAVLVTGADSGFGHGLAKHLDKLG--FTVFAGVLDKEGPGAEELRKHCSERLSVL 136

  Fly   108 DVDFTGGDEIYD---KIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSV 169
            .:|.|..::|.|   |:.||.....:..:|||.|: :..|   :|.........|..:|.|....
Mouse   137 QMDVTKPEQIKDAHSKVTEKIQDKGLWAVVNNAGV-FHLP---IDGELIPMSIYRKCMAVNFFGT 197

  Fly   170 THMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSV 234
            ..:|..||| ::.:.:|.::||||..|.:|..:.|.|::|||.:..||..::.|..:.|:.:.::
Mouse   198 VEVTKAFLP-LLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAALTMFSTIIRQELDKWGVKVVTI 261

  Fly   235 QPGFVATNMS 244
            :||...||::
Mouse   262 KPGGFKTNIT 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	56/197 (28%)
Hsd17b2	NP_032316.2	type2_17beta_HSD-like_SDR_c	84..364	CDD:187665	56/195 (29%)