Protein Alignment spidey and Hsd17b11

DIOPT Version :10

• Sequence 1: NP_572420.1
• Gene: spidey / 31703
• FlyBaseID: FBgn0029975
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_444492.1
• Gene: Hsd17b11 / 114664
• MGIID: 2149821
• Length: 298
• Species: Mus musculus
• Alignment Length: 281
• Identity: 75/281 - (26%)
• Similarity: 123/281 - (43%)
• Gaps: 26/281 - (9%)

  Fly    40 KVFGSSVDLSKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEV 104
            |:|......|..||..::||:..|||:..|.|.|:...||||...:...:...|.:. .|.|.:.
Mouse    24 KLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKC-RKLGAQA 87

  Fly   105 RVIDVDFTGGDEIYD---KIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANI 166
            ....||.:..:|||.   |::|:..  :|.:||||.|:     .|..|.:....|.:......|:
Mouse    88 HPFVVDCSQREEIYSAAKKVKEEVG--DVSILVNNAGV-----VYTADLFATQDPQIEKTFEVNV 145

  Fly   167 HSVTHMTALFLPGMISQRRGVIINVSSTAGVIPNPLLSVYSSTK----AFVNKFSDDLQTEYKEH 227
            .:....|..|||.|:....|.|:.|:|.||....|.|..|.|:|    .|....:|:| ......
Mouse   146 LAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDEL-AALGRT 209

  Fly   228 GILIQSVQPGFVATNMSKIRKASVFAPS--PETYVRSALSTLGIATQTAG-YLPHALLQLVIHFT 289
            |:....:.|.|:.|...| ..::...|:  ||..|...:.  ||.|:... ::|.::..|.:  .
Mouse   210 GVRTSCLCPNFINTGFIK-NPSTNLGPTLEPEEVVEHLMH--GILTEKQMIFVPSSIALLTV--L 269

  Fly   290 EAVFGEQFARNIVMKNILGTR 310
            |.:..|:|.:  |:|:.:..:
Mouse   270 ERIVPERFLQ--VLKHRINVK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spidey	NP_572420.1	17beta-HSD1_like_SDR_c	52..288	CDD:187614	67/245 (27%)
Hsd17b11	NP_444492.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	67/252 (27%)