DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and KIRREL2

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_954649.3	Gene:	KIRREL2 / 84063	HGNCID:	18816	Length:	708	Species:	Homo sapiens

Alignment Length:	216	Identity:	50/216 - (23%)
Similarity:	70/216 - (32%)	Gaps:	36/216 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 PFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLE 135
            |.|.|......|.:  .|.....|.|.:....| .|.|.:.     .|...||....|.|||.:.
Human    22 PSPHFLQQPEDLVV--LLGEEARLPCALGAYWG-LVQWTKS-----GLALGGQRDLPGWSRYWIS 78

  Fly   136 FEEPN-DWKLLIQFANERDEGPYECQVS-----SHPPLVLLVYLTIIVP--HVEILDERGSATPE 192
            ....| ...|.|:.....||..||||.:     |.|     ..|.::||  ..::|     ..|.
Human    79 GNAANGQHDLHIRPVELEDEASYECQATQAGLRSRP-----AQLHVLVPPEAPQVL-----GGPS 133

  Fly   193 KYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDML----PGRALSRLYIA 253
            ....||....|.|.......|:..:.|.....||:      |.:....:|    ||...|.|.:.
Human   134 VSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLD------GATFHQTLLKEGTPGSVESTLTLT 192

  Fly   254 NANRQDTGNYTCMLGNEITET 274
            ..:..|...:.|...::...|
Human   193 PFSHDDGATFVCRARSQALPT 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	22/85 (26%)
		Ig	84..169	CDD:299845	24/90 (27%)
		IG_like	191..279	CDD:214653	18/88 (20%)
		Ig	201..274	CDD:143165	14/76 (18%)
KIRREL2	NP_954649.3	IG_like	30..119	CDD:214653	26/101 (26%)
		IGc2	38..106	CDD:197706	21/73 (29%)
		I-set	126..224	CDD:254352	19/99 (19%)
		Ig2_KIRREL3-like	141..223	CDD:143236	15/79 (19%)
		Cell attachment site. /evidence=ECO:0000255	149..151		0/1 (0%)
		Ig	231..306	CDD:299845
		IG_like	234..308	CDD:214653
		Ig	312..395	CDD:299845
		I-set	317..395	CDD:254352
		Ig	397..501	CDD:299845
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	545..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810