Protein Alignment dpr14 and CADM3

DIOPT Version :9

• Sequence 1: NP_001245573.1
• Gene: dpr14 / 31702
• FlyBaseID: FBgn0029974
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_024304528.1
• Gene: CADM3 / 57863
• HGNCID: 17601
• Length: 481
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 62/333 - (18%)
• Similarity: 111/333 - (33%)
• Gaps: 113/333 - (33%)

  Fly    76 ADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPN 140
            :.|:|: :.:.....:|.|.|:|.|.:..::.|.......|   .||:.....|:|..|....|:
Human   114 SQPWTS-DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTL---YFGEKRALRDNRIQLVTSTPH 174

  Fly   141 DWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTII-VPHVEILDERGSATPEKYYKAGSTIELQ 204
            :..:.|......|||.|.|.:.:.|.......:|:: :|...|:....|:..||     .|..|.
Human   175 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK-----DTATLN 234

  Fly   205 CVISKIPHPSSYITWRHGPRLLNYDTSR-------------------------GG---ISVKTDM 241
            |. |....|::.:|||.|.:.|:.:.:|                         |.   .||..:.
Human   235 CQ-SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHES 298

  Fly   242 LPG--RALSR----LYIANA--------------------------------------------- 255
            |.|  |:.|:    ||...|
Human   299 LKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQ 363

  Fly   256 ---------NRQDTGNYTCMLGNEITETVVVHVLNGEEPAAMQHANGSRQKANASTM------VV 305
                     |:.|:|.|.|...:.:......:.||..:|:.:        .:::||.      :|
Human   364 ESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV--------PSSSSTYHAIIGGIV 420

  Fly   306 LFLVYVCI 313
            .|:|::.:
Human   421 AFIVFLLL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	19/79 (24%)
		Ig	84..169	CDD:299845	20/84 (24%)
		IG_like	191..279	CDD:214653	28/175 (16%)
		Ig	201..274	CDD:143165	25/160 (16%)
CADM3	XP_024304528.1	Ig1_Necl-1	115..209	CDD:143290	22/97 (23%)
		Ig2_Necl-1	230..312	CDD:143329	18/82 (22%)
		IG_like	328..399	CDD:214653	6/70 (9%)
		4.1m	437..452	CDD:128590

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I5236
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960