DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and igsf9b

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_686205.6	Gene:	igsf9b / 553348	ZFINID:	ZDB-GENE-060810-28	Length:	2021	Species:	Danio rerio

Alignment Length:	288	Identity:	64/288 - (22%)
Similarity:	95/288 - (32%)	Gaps:	85/288 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 STTLKRPRAGDPFDTFPKNFWQEFSSPFTDTPEDEELEVTETT---------------------- 67
            |.||.....|:|..|.   .|:::.|.   ..:.||::|...|
Zfish   158 SLTLHCDAHGNPKPTI---IWRKYLSA---AEKQEEIQVLNETLSLSKVTRETAGIYKCHVSNSE 216

  Fly    68 ---THE--------PFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGK-TVSWMRRRGDDLTLIT 120
               ||.        |....|...||:|    :|....|.|:....... |..|.::
Zfish   217 GNLTHSTQLQVKGPPIIIIAPEDTTMN----MSQDAVLQCQAEAYPSNLTYEWWKQ--------- 268

  Fly   121 FGQHTYSGD---SRYSLEFEEPNDWKLLIQFANERDEGPYECQVSS---HPPLVLLVYLTIIVPH 179
             ||:.|..:   ||..:..    |..|||......|.|.|.|:.::   .|| ....|||:..|.
Zfish   269 -GQNVYHIEILKSRVKILV----DGTLLISALIPDDSGNYTCRPTNGLMTPP-AASAYLTVKHPA 327

  Fly   180 VEILDERGSATPEKYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPG 244
            ..:...|     |.|...|...::.|.:...| |..|:.|           ::.|.|:..:..||
Zfish   328 RVVRMPR-----ETYLPMGMGGKIPCPVQAEP-PMLYVNW-----------TKDGASLNLEQYPG 375

  Fly   245 ---RALSRLYIANANRQDTGNYTCMLGN 269
               .:...::|..||....|.|||...|
Zfish   376 WMVNSEGSVFITAANDDAVGMYTCTAYN 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	19/83 (23%)
		Ig	84..169	CDD:299845	20/91 (22%)
		IG_like	191..279	CDD:214653	20/82 (24%)
		Ig	201..274	CDD:143165	17/72 (24%)
igsf9b	XP_686205.6	Ig	27..132	CDD:299845
		IG_like	148..227	CDD:214653	14/74 (19%)
		IGc2	156..217	CDD:197706	12/64 (19%)
		Ig	237..323	CDD:299845	25/104 (24%)
		IG_like	237..323	CDD:214653	25/104 (24%)
		Ig	345..411	CDD:143165	17/71 (24%)
		IG_like	435..507	CDD:214653
		IGc2	437..496	CDD:197706
		FN3	512..603	CDD:238020
		FN3	621..709	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910