Protein Alignment dpr14 and NTM

DIOPT Version :10

• Sequence 1: NP_572419.1
• Gene: dpr14 / 31702
• FlyBaseID: FBgn0029974
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001338930.1
• Gene: NTM / 50863
• HGNCID: 17941
• Length: 367
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 67/349 - (19%)
• Similarity: 119/349 - (34%)
• Gaps: 128/349 - (36%)

  Fly    72 FPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEF 136
            ||...|     |::.:...|..|.|.: |.:...|:|:.|.    |::..|...:..|.|..|..
Human    38 FPKAMD-----NVTVRQGESATLRCTI-DNRVTRVAWLNRS----TILYAGNDKWCLDPRVVLLS 92

  Fly   137 EEPNDWKLLIQFANERDEGPYEC--QVSSHPPLVLLVYLTIIVPH-VEILDERGSATPEKYYKAG 198
            .....:.:.||..:..|||||.|  |..:||....:..:..:.|. |||       :.:.....|
Human    93 NTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI-------SSDISINEG 150

  Fly   199 STIELQCVISKIPHPSSYITWRH-GPRLL--------------------NYDTS----------- 231
            :.|.|.|:.:..|.|:  :|||| .|:.:                    :|:.|
Human   151 NNISLTCIATGRPEPT--VTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVR 213

  Fly   232 ------------------------RGGISVKTDMLPGRA------------------------LS 248
                                    :|.:..:...:|...                        ||
Human   214 RVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLS 278

  Fly   249 RLYIANANRQDTGNYTCMLGNEITET---VVVHVLNGEEP---------------------AAMQ 289
            :|...|.:..|.|||||:..|::..|   :::..||  ||                     |..:
Human   279 KLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELN--EPTSSTLLQEVKTTALTPWKGPGAVSE 341

  Fly   290 HANGSRQKANASTMVVLFLVYVCI 313
            .:||:.::|....::.|.::::.:
Human   342 VSNGTSRRAGCVWLLPLLVLHLLL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_572419.1	Ig	81..175	CDD:472250	24/95 (25%)
		Ig strand B	92..96	CDD:409353	1/3 (33%)
		Ig strand C	105..109	CDD:409353	1/3 (33%)
		Ig strand E	142..146	CDD:409353	0/3 (0%)
		Ig strand F	156..161	CDD:409353	3/6 (50%)
		Ig strand G	168..171	CDD:409353	0/2 (0%)
		IG_like	191..279	CDD:214653	27/170 (16%)
		Ig strand B	201..205	CDD:409473	2/3 (67%)
		Ig strand C	214..220	CDD:409473	1/5 (20%)
		Ig strand E	248..252	CDD:409473	2/3 (67%)
		Ig strand F	262..267	CDD:409473	4/4 (100%)
NTM	NP_001338930.1	Ig	44..132	CDD:472250	24/92 (26%)
		Ig strand B	53..57	CDD:409353	1/3 (33%)
		Ig strand C	65..69	CDD:409353	1/3 (33%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	3/4 (75%)
		Ig strand G	125..128	CDD:409353	0/2 (0%)
		Ig_3	136..205	CDD:464046	17/77 (22%)
		Ig	223..307	CDD:472250	14/83 (17%)
		Ig strand B	239..243	CDD:409353	1/3 (33%)
		Ig strand C	252..256	CDD:409353	0/3 (0%)
		Ig strand E	278..282	CDD:409353	2/3 (67%)
		Ig strand F	292..297	CDD:409353	4/4 (100%)