DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and tutl

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	82/430 - (19%)
Similarity:	126/430 - (29%)	Gaps:	170/430 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IIYSSLHHIGSGSTSTTLKRPRAGDPFDTFPKNFWQEFSSPFTDTP------EDEELEVTETTTH 69
            |||.:|      ..|..|.....|.|   .|:..|.:.::|...:|      :..||.:: |..|
  Fly   262 IIYVNL------GDSIILNCQADGTP---TPEILWYKDANPVDPSPTVGIFNDGTELRIS-TIRH 316

  Fly    70 EPFPFFADPYTTL--NISTQLS-------------------------SSVYLHCRVNDLQGK-TV 106
            |..    ..||.:  |...|:|                         ..|...|....:.|. ||
  Fly   317 EDI----GEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTV 377

  Fly   107 SWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWKLLIQFANERDEGPYECQVSS--HPPLVL 169
            .|. |.|..:      :...:.::|.::.    .|..|:|......|.|.|.|:|::  ..|...
  Fly   378 RWY-REGSPV------REVAALETRVTIR----KDGSLIINPIKPDDSGQYLCEVTNGIGDPQSA 431

  Fly   170 LVYLTIIVPHVEILDERGSATPEKYY----KAGSTIELQCVISKIPHPSSYITWRHGPRLLN--- 227
            ..||::..|      .:.:.||...|    .||   .:||.|...|. ..|:||....|||.
  Fly   432 SAYLSVEYP------AKVTFTPTVQYLPFRLAG---VVQCYIKSSPQ-LQYVTWTKDKRLLEPYQ 486

  Fly   228 -----------------------------------------------------------YDTSRG 233
                                                                       |....|
  Fly   487 MKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVG 551

  Fly   234 -GISVKTDMLPGRALSR---------------------------LYIANANRQDTGNYTCMLGNE 270
             .:.:..|.|......|                           :.|.|..|:|.|.|.|::.||
  Fly   552 DSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNE 616

  Fly   271 ITETVVVH--VLNGEEPAAMQHANGSRQKANASTMVVLFL 308
            :...:.|.  |:.|.:|.|..:..|   ||..|::.:.:|
  Fly   617 VATLMAVTQLVIEGTQPHAPYNITG---KATESSITLQWL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	20/105 (19%)
		Ig	84..169	CDD:299845	20/112 (18%)
		IG_like	191..279	CDD:214653	29/183 (16%)
		Ig	201..274	CDD:143165	24/162 (15%)
tutl	NP_001303307.1	V-set	137..250	CDD:284989
		IG_like	137..229	CDD:214653
		I-set	253..341	CDD:254352	22/92 (24%)
		IGc2	268..331	CDD:197706	16/70 (23%)
		I-set	346..437	CDD:254352	20/101 (20%)
		Ig	349..437	CDD:299845	20/98 (20%)
		Ig	459..530	CDD:299845	10/71 (14%)
		IG_like	549..628	CDD:214653	14/78 (18%)
		IGc2	551..617	CDD:197706	12/65 (18%)
		FN3	633..725	CDD:238020	7/24 (29%)
		FN3	786..874	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810