DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and opcml

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	314	Identity:	69/314 - (21%)
Similarity:	111/314 - (35%)	Gaps:	95/314 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPND 141
            |.|...||:.:...|..|.|.: |.:...|:|:.|    .|::..|...:|.|.|..|.....|:
Zfish    35 DSYLKDNITVRQGDSAVLKCSM-DNKVSRVAWLNR----TTILFTGNEKWSLDPRVVLLNTAVNE 94

  Fly   142 WKLLIQFANERDEGPYECQV-SSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIELQC 205
            :.:.|...|..|||||.|.: ::..|....|:|.:.|| ..|:    :.:.:.....||.:.|.|
Zfish    95 YSIKILNVNLYDEGPYVCSILTNKKPESTKVHLIVQVP-ARIV----NVSTDVSVNEGSNVSLMC 154

  Fly   206 VISKIPHPSSYITWR----HGPRLL-----------------NYD--TS---------------- 231
            :....|.||  |.|:    .|.|::                 :||  ||
Zfish   155 LAIGRPEPS--ILWKFRSSKGNRIVTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVN 217

  Fly   232 -----------------RGGISVKTDMLP----------GRAL--------------SRLYIANA 255
                             :|.:..:...:|          .|.|              |.|...|.
Zfish   218 YPPVISRARSTGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNGVKIENKGKQSMLTFFNV 282

  Fly   256 NRQDTGNYTCMLGNEITETVVVHVLNGEEPAAMQHANGSRQKANASTMVVLFLV 309
            :.:|.|||||:..|.:..|....:|.|  |.|:...|.:......|.:::..|:
Zfish   283 SEEDYGNYTCVAINTLGITNASIILYG--PGAIHDVNNAALSPTCSLLLLTLLL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	24/80 (30%)
		Ig	84..169	CDD:299845	24/85 (28%)
		IG_like	191..279	CDD:214653	30/167 (18%)
		Ig	201..274	CDD:143165	27/152 (18%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	27/92 (29%)
		IG_like	41..129	CDD:214653	27/92 (29%)
		IG_like	139..216	CDD:214653	15/78 (19%)
		IGc2	146..202	CDD:197706	14/57 (25%)
		I-set	219..307	CDD:254352	15/87 (17%)
		ig	223..307	CDD:278476	15/83 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810