DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr14 and klg

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	69/289 - (23%)
Similarity:	97/289 - (33%)	Gaps:	80/289 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LFWILAIIYSSLH-HIGSGSTSTTLKRPRAGDPFDTFPKNFWQEFSSPFTDTPEDEELEVTETTT 68
            |.|:       || |.|||..:........|..            |...::..:......|.|.|
  Fly    54 LGWL-------LHAHAGSGGFAVEAAISNRGSN------------SRSMSNVQQSAVAASTLTAT 99

  Fly    69 HEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSR-- 131
            ...|......|..:     :..::.|.|:|.:|....:.|  |||.:  ::|......:.|.|
  Fly   100 LPRFLSRGHTYRAV-----VGDTLVLPCQVENLGNFVLLW--RRGTN--VLTASNIMVTRDERVR 155

  Fly   132 ----YSLEFE--EPNDWKLLIQFANERDEGPYECQVSS-------HPPLVLLVYLTIIVPHVEIL 183
                |:||..  ||            :|.|.|.||:|.       |...:|      :.|.|..:
  Fly   156 LIDGYNLEISDLEP------------QDAGDYVCQISDKINRDQVHTVEIL------VPPSVRAI 202

  Fly   184 DERGSATPEKYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALS 248
            ...|.....|    |..|.|:|..|..|.||.|.|.:.|   .|..|:|.|..      |...|.
  Fly   203 PTSGQLQARK----GGPITLECKGSGNPVPSIYWTKKSG---ANKSTARIGDG------PILTLE 254

  Fly   249 RLYIANANRQDTGNYTCMLGNEITETVVV 277
            :|     .||..|.|.|...|.:.:.|.|
  Fly   255 KL-----ERQQAGVYQCTADNGVGDPVTV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	21/87 (24%)
		Ig	84..169	CDD:299845	23/99 (23%)
		IG_like	191..279	CDD:214653	27/87 (31%)
		Ig	201..274	CDD:143165	23/72 (32%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	12/77 (16%)
		IG_like	109..195	CDD:214653	25/112 (22%)
		Ig	118..191	CDD:143165	23/88 (26%)
		IG_like	205..274	CDD:214653	26/86 (30%)
		IGc2	213..273	CDD:197706	24/73 (33%)
		IGc2	301..367	CDD:197706
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810