DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and LSAMP

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001305844.1	Gene:	LSAMP / 4045	HGNCID:	6705	Length:	361	Species:	Homo sapiens

Alignment Length:	205	Identity:	59/205 - (28%)
Similarity:	83/205 - (40%)	Gaps:	37/205 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 TLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWKLL 145
            |.||:.:...:..|.|.|.|...| |:|:.|.|    :|..|...:|.|.|..||.....::.|.
Human    38 TDNITVRQGDTAILRCVVEDKNSK-VAWLNRSG----IIFAGHDKWSLDPRVELEKRHSLEYSLR 97

  Fly   146 IQFANERDEGPYECQV-SSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIELQCVISK 209
            ||..:..|||.|.|.| :.|.|....|||.:.||     .:..:.:.:.....||.:.|.|:.:.
Human    98 IQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVP-----PKISNISSDVTVNEGSNVTLVCMANG 157

  Fly   210 IPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLP-GRAL----SRLYIANANRQDTGNYTCMLGN 269
            .|.|  .|||||                   :.| ||..    ..|.|....|:.:|.|.|...|
Human   158 RPEP--VITWRH-------------------LTPTGREFEGEEEYLEILGITREQSGKYECKAAN 201

  Fly   270 EITETVVVHV 279
            |::...|..|
Human   202 EVSSADVKQV 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	27/80 (34%)
		Ig	84..169	CDD:299845	28/85 (33%)
		IG_like	191..279	CDD:214653	23/92 (25%)
		Ig	201..274	CDD:143165	20/77 (26%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:386229	33/94 (35%)
		Ig	132..215	CDD:386229	24/101 (24%)
		Ig_3	219..294	CDD:372822
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810