DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and wrapper

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	51/216 - (23%)
Similarity:	84/216 - (38%)	Gaps:	41/216 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWKL---- 144
            :.|..:.:|.|.|.:| ...:.|.|.|   ||:.|:         |||:. |...|:...|
  Fly    44 VKTYENDTVQLPCTLN-TPFRYVRWHR---DDVALV---------DSRHP-ELPPPDRIMLWPNG 94

  Fly   145 LIQFAN--ERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIELQCVI 207
            .:|.||  ..|.|.|.|:::|....|:..:...:....::|.|....|.:   :.|:..|:.|..
  Fly    95 SLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQ---RIGAIFEVVCEA 156

  Fly   208 SKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYTCMLGNEIT 272
            ..:|.|  .||||....::...::.|.            ...|.:...:|...|...|:..|.:.
  Fly   157 QGVPQP--VITWRLNGNVIQPQSNTGN------------RQSLILEIKSRNQAGLIECVASNGVG 207

  Fly   273 E----TVVVHVLNGEEPAAMQ 289
            |    .|.:|||...|.:..|
  Fly   208 EPAVANVYLHVLFSPEVSIPQ 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	24/84 (29%)
		Ig	84..169	CDD:299845	25/90 (28%)
		IG_like	191..279	CDD:214653	17/91 (19%)
		Ig	201..274	CDD:143165	15/76 (20%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	26/93 (28%)
		IG_like	41..118	CDD:214653	25/87 (29%)
		IG_like	145..218	CDD:214653	17/86 (20%)
		Ig	147..219	CDD:299845	18/85 (21%)
		I-set	224..323	CDD:254352	1/5 (20%)
		IGc2	236..314	CDD:197706
		FN3	339..431	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900