DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr14 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	60/211 - (28%)
Similarity:	97/211 - (45%)	Gaps:	20/211 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFE 137
            |.|:.|..  |.:..:.....|.|.|:||....|:|:  |.|..|:::...|..:.:.|.|:...
  Fly    31 PKFSGPIN--NSTVPVGRDALLTCVVHDLVSFKVAWL--RVDTQTILSIQNHVITKNHRISISHT 91

  Fly   138 EPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIE 202
            |...|:|.|:...|.|.|.|.||:::.|....:.||.::|| .:|:|.:.|  .:.....|..:.
  Fly    92 EHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVP-PDIVDYQTS--QDVVRSTGQNVT 153

  Fly   203 LQCVISKIPHPSSYITWRH---GPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYT 264
            |.|..:.:|.|:  ||||.   .|.|::.|..|...||:     |:.|:   :....|...|.|.
  Fly   154 LTCSATGVPMPT--ITWRREEATPILISDDGDREVFSVE-----GQNLT---LWQVQRSHMGAYL 208

  Fly   265 CMLGNEITETVVVHVL 280
            |:..|.:..||...|:
  Fly   209 CIASNGVPPTVSKRVM 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	24/79 (30%)
		Ig	84..169	CDD:299845	24/84 (29%)
		IG_like	191..279	CDD:214653	24/90 (27%)
		Ig	201..274	CDD:143165	21/75 (28%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	25/87 (29%)
		Ig	39..122	CDD:299845	25/84 (30%)
		Ig	132..213	CDD:299845	25/93 (27%)
		IG_like	141..227	CDD:214653	26/96 (27%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810