DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and DIP-beta

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	92/221 - (41%)	Gaps:	37/221 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVS-----------WMRRRGDDLTLITFGQHTY 126
            |.|..|..  |::..........|.||:|.|..||           |:  :.|...::...:|..
  Fly    98 PDFVIPLE--NVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWI--KADAKAILAIHEHVI 158

  Fly   127 SGDSRYSLEFEEPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSA-- 189
            :.:.|.|::..:.|.|.|.|:.....|.|.|.|||::.|..:....|.:::| .:|::|..|.
  Fly   159 TNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIP-PDIINEETSGDM 222

  Fly   190 -TPEKYYKAGSTIELQCVISKIPHPSSYITWRH--GPRLLNYDTSRGGISVKT--DMLPGRALSR 249
             .||     |.:.:|.|  ....||...||||.  |..::    :|.|...||  ..:.|..|:
  Fly   223 MVPE-----GGSAKLVC--RARGHPKPKITWRREDGREII----ARNGSHQKTKAQSVEGEMLT- 275

  Fly   250 LYIANANRQDTGNYTCMLGNEITETV 275
              ::...|.:.|.|.|:..|.:..||
  Fly   276 --LSKITRSEMGAYMCIASNGVPPTV 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	23/90 (26%)
		Ig	84..169	CDD:299845	23/95 (24%)
		IG_like	191..279	CDD:214653	25/89 (28%)
		Ig	201..274	CDD:143165	20/76 (26%)
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	28/114 (25%)
		ig	102..195	CDD:278476	24/96 (25%)
		IG_like	219..307	CDD:214653	26/95 (27%)
		Ig	221..307	CDD:299845	25/93 (27%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810