DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr14 and Negr1

DIOPT Version :9

Sequence 1:NP_001245573.1 Gene:dpr14 / 31702 FlyBaseID:FBgn0029974 Length:340 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:308 Identity:67/308 - (21%)
Similarity:108/308 - (35%) Gaps:80/308 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 FPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEF 136
            ||:.|    ..|:..:...:..|.|.:.|...|. :|:.|.    ::|..|...:|.|.|.|:..
Mouse    34 FPWAA----VDNMLVRKGDTAVLRCYLEDGASKG-AWLNRS----SIIFAGGDKWSVDPRVSIST 89

  Fly   137 EEPNDWKLLIQFANERDEGPYECQV-SSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGST 200
            ....|:.|.||..:..|:|||.|.| :.|.|..:.|:||:.|| .:|.|.....|    ...|:.
Mouse    90 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVP-PKIYDISNDMT----INEGTN 149

  Fly   201 IELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYTC 265
            :.|.|:.:..|.|  .|:|||               :.....|......|.|....|...|.|.|
Mouse   150 VTLTCLATGKPEP--VISWRH---------------ISPSAKPFENGQYLDIYGITRDQAGEYEC 197

  Fly   266 MLGNEIT--ETVVVHVL---------------------------NGEEPAAMQHANGSRQKANAS 301
            ...|:::  :...|.|:                           .|..|.|.:...|.::..|..
Mouse   198 SAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQ 262

  Fly   302 TMVVL------------------FLVYVCISGSISVAGMNRGLGLGQV 331
            ..:::                  |..|.|::.: .:...|..|.|.|:
Mouse   263 QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAAN-KLGTTNASLPLNQI 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr14NP_001245573.1 IG_like 83..163 CDD:214653 23/80 (29%)
Ig 84..169 CDD:299845 24/85 (28%)
IG_like 191..279 CDD:214653 18/89 (20%)
Ig 201..274 CDD:143165 16/74 (22%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 3/20 (15%)
Ig strand A' 40..46 CDD:409353 1/5 (20%)
IG_like 41..129 CDD:214653 27/92 (29%)
Ig strand B 48..56 CDD:409353 2/7 (29%)
CDR1 56..60 CDD:409353 1/3 (33%)
FR2 61..68 CDD:409353 2/7 (29%)
Ig strand C 61..67 CDD:409353 2/6 (33%)
CDR2 69..79 CDD:409353 2/13 (15%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 13/34 (38%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 2/5 (40%)
Ig strand F 107..115 CDD:409353 4/7 (57%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 3/8 (38%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 1/8 (13%)
IGc2 146..204 CDD:197706 17/74 (23%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 8/75 (11%)
putative Ig strand A 219..225 CDD:409353 0/5 (0%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 1/3 (33%)
Ig strand E 274..278 CDD:409353 0/3 (0%)
Ig strand F 288..293 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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