DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and Kirrel3

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_038937320.1	Gene:	Kirrel3 / 315546	RGDID:	1311382	Length:	869	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	62/282 - (21%)
Similarity:	98/282 - (34%)	Gaps:	73/282 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 THEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRY 132
            |.||.....|          |.|.....|........|:.|| :||..:.|
  Rat   338 TSEPQSLLVD----------LGSDAVFSCAWIGNPSLTIVWM-KRGSGVVL-------------- 377

  Fly   133 SLEFEEPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHV-----EI-LDERG---- 187
                  .|:..|.::...:.|.|.|.|:.              :||.|     |: |...|
  Rat   378 ------SNEKTLTLKSVRQEDAGKYVCRA--------------VVPRVGAGEREVTLTVNGPPII 422

  Fly   188 SATPEKYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYI 252
            |:|..::...|...:::|.|...| |...|.|.....:|...|| |..:|:|.......:|.|.|
  Rat   423 SSTQTQHALHGEKGQIKCFIRSTP-PPDRIAWSWKENVLESGTS-GRYTVETVNTEEGVISTLTI 485

  Fly   253 ANANRQDTGN-YTCMLGNEI-TETVVVHVLNGEEPAAMQHANGSRQKANASTMVVL--------- 306
            :|..|.|... |.|...|.. ::|.::.:  .|:.:.|:  :|:..:|.:..|.|:
  Rat   486 SNIVRADFQTIYNCTAWNSFGSDTEIIRL--KEQGSEMK--SGAGLEAESVPMAVIIGVAVGAGV 546

  Fly   307 -FLVYVCISGSISVAGMNRGLG 327
             |||.:....:...|...|..|
  Rat   547 AFLVLMATIVAFCCARSQRSTG 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	15/79 (19%)
		Ig	84..169	CDD:299845	15/84 (18%)
		IG_like	191..279	CDD:214653	23/89 (26%)
		Ig	201..274	CDD:143165	21/74 (28%)
Kirrel3	XP_038937320.1	IG_like	54..143	CDD:214653
		Ig strand A'	56..60	CDD:409353
		Ig strand B	64..71	CDD:409353
		Ig strand C	78..82	CDD:409353
		Ig strand C'	84..87	CDD:409353
		Ig strand D	97..101	CDD:409353
		Ig strand E	104..116	CDD:409353
		Ig strand G	132..143	CDD:409353
		IgI_2_KIRREL3-like	149..246	CDD:409416
		Ig strand B	166..170	CDD:409416
		Ig strand C	180..184	CDD:409416
		Ig strand E	210..214	CDD:409416
		Ig strand F	224..229	CDD:409416
		Ig strand G	239..242	CDD:409416
		Ig	<267..334	CDD:416386
		Ig strand B	267..274	CDD:409353
		Ig strand C	279..286	CDD:409353
		Ig strand C'	288..291	CDD:409353
		Ig strand D	298..302	CDD:409353
		Ig strand E	304..310	CDD:409353
		Ig strand G	321..334	CDD:409353
		Ig	335..416	CDD:416386	24/122 (20%)
		Ig strand A'	343..347	CDD:409353	0/3 (0%)
		Ig strand B	350..360	CDD:409353	2/9 (22%)
		Ig strand C	365..371	CDD:409353	3/6 (50%)
		Ig strand E	381..387	CDD:409353	1/5 (20%)
		IgI_5_KIRREL3	418..515	CDD:409479	26/100 (26%)
		Ig strand B	436..440	CDD:409479	0/3 (0%)
		Ig strand C	450..454	CDD:409479	1/3 (33%)
		Ig strand E	481..485	CDD:409479	2/3 (67%)
		Ig strand F	496..501	CDD:409479	2/4 (50%)
		Ig strand G	509..512	CDD:409479	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810