DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and DIP-alpha

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	50/207 - (24%)
Similarity:	91/207 - (43%)	Gaps:	20/207 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFE 137
            |.|.:..:  |:|..:.......|.|..|.|..|.|:  :.|...:....::..:.:.|.::...
  Fly    42 PEFVESIS--NVSVAVGRDATFTCHVRHLGGYRVGWL--KADTKAIQAIHENVITHNPRVTVSHL 102

  Fly   138 EPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGS--ATPEKYYKAGST 200
            :.|.|.|.|:..:|.|.|.|.||:::.|....:.:|.:::|...|.::..|  ..||     ||:
  Fly   103 DQNTWNLHIKAVSEEDRGGYMCQLNTDPMKSQIGFLDVVIPPDFISEDTSSDVIVPE-----GSS 162

  Fly   201 IELQCVISKIPHPSSYITWRH--GPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNY 263
            :.|.|.....|.|  .:|||.  |..::..|    .:..|| :.|......|.::..:|.:.|:|
  Fly   163 VRLTCRARGYPEP--IVTWRREDGNEIVLKD----NVGTKT-LAPSFRGEVLKLSKISRNEMGSY 220

  Fly   264 TCMLGNEITETV 275
            .|:..|.:..:|
  Fly   221 LCIASNGVPPSV 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	20/79 (25%)
		Ig	84..169	CDD:299845	20/84 (24%)
		IG_like	191..279	CDD:214653	23/87 (26%)
		Ig	201..274	CDD:143165	18/74 (24%)
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653	20/83 (24%)
		Ig	51..131	CDD:299845	19/81 (23%)
		I-set	144..240	CDD:254352	25/101 (25%)
		IGc2	159..228	CDD:197706	21/80 (26%)
		Ig	244..337	CDD:299845
		I-set	244..337	CDD:254352
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810