DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and kirre

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	78/312 - (25%)
Similarity:	109/312 - (34%)	Gaps:	96/312 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SLHHIGSGSTSTTL-----------------KRPRAGDPFDTFPKNFWQEFSSPFTDTPEDEELE 62
            |.||..|.|:|::.                 .:|:.||       |..|.|:.    .|:|:
  Fly    41 SSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGD-------NGGQHFAM----EPQDQ--- 91

  Fly    63 VTETTTHEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQH-TY 126
                                  :..:.|.|.|.|||.:..| .:.|.:   ||..|   ||| ..
  Fly    92 ----------------------TAVVGSRVTLPCRVMEKVG-ALQWTK---DDFGL---GQHRNL 127

  Fly   127 SGDSRYSL-EFEEPNDWKLLIQFANERDEGPYECQVSSHPP-----LVLLVYLTIIVPHVEILDE 185
            ||..|||: ..:|..|:.|.|......|:..|:|||...|.     ......||::||     .|
  Fly   128 SGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVP-----PE 187

  Fly   186 RGSATPEKYY--KAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGR--- 245
            ....|...|.  .....|||:|| |:...|::.|||..|   |....::|...||..:...|
  Fly   188 APKITQGDYLVTTEDREIELECV-SQGGKPAAEITWIDG---LGNVLTKGIEYVKEPLADSRRIT 248

  Fly   246 ALSRLYIANANRQDTGNYTCMLGNEITET---------------VVVHVLNG 282
            |.|.|.:|.........:||...|....|               |:|.|:.|
  Fly   249 ARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGG 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	28/81 (35%)
		Ig	84..169	CDD:299845	29/91 (32%)
		IG_like	191..279	CDD:214653	27/107 (25%)
		Ig	201..274	CDD:143165	23/75 (31%)
kirre	NP_001245505.1	Ig	87..183	CDD:299845	33/127 (26%)
		IG_like	88..182	CDD:214653	32/125 (26%)
		C2-set_2	189..279	CDD:285423	26/93 (28%)
		Ig_2	307..379	CDD:290606
		I-set	382..462	CDD:254352
		IGc2	396..446	CDD:197706
		Ig	466..561	CDD:299845
		IG_like	478..561	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810