DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and Lrit1

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_666357.2	Gene:	Lrit1 / 239037	MGIID:	2385320	Length:	624	Species:	Mus musculus

Alignment Length:	162	Identity:	36/162 - (22%)
Similarity:	53/162 - (32%)	Gaps:	36/162 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WILAIIYSSLHHIGSGSTSTTL----KRPRAGDPFDTFPKNFWQEFSSPFTDTPEDEELEVTETT 67
            |:.......|.|:..|..|:.|    .|.|...|.......|              .:||:.:..
Mouse   203 WVCDCRLYDLVHLLDGWVSSNLIFIEARLRCASPRSLAGVAF--------------SQLELRKCQ 253

  Fly    68 THEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRY 132
            :.|..|      ...:|.:.|.|:|.|.|....:.|..:||.|..|..|......:.:..|.|
Mouse   254 SPELRP------GVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNGTVHQEVSSDGSS-- 310

  Fly   133 SLEFEEPNDWKLL-IQFANERDEGPYECQVSS 163
                     |.|| :...:..|.|.|.||..:
Mouse   311 ---------WTLLDLPVVSLFDSGDYICQAKN 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	22/80 (28%)
		Ig	84..169	CDD:299845	22/81 (27%)
		IG_like	191..279	CDD:214653
		Ig	201..274	CDD:143165
Lrit1	NP_666357.2	LRRNT	23..61	CDD:214470
		LRR 1	60..81
		LRR_8	63..143	CDD:290566
		leucine-rich repeat	64..84	CDD:275378
		LRR 2	84..105
		leucine-rich repeat	85..132	CDD:275378
		LRR 3	108..129
		LRR_8	131..>176	CDD:290566
		LRR_4	131..172	CDD:289563
		LRR 4	132..153
		leucine-rich repeat	133..156	CDD:275378
		LRR 5	156..177
		leucine-rich repeat	157..180	CDD:275378
		leucine-rich repeat	181..205	CDD:275378	1/1 (100%)
		TPKR_C2	201..>241	CDD:301599	9/37 (24%)
		Ig	258..346	CDD:299845	23/93 (25%)
		IG_like	268..346	CDD:214653	21/77 (27%)
		FN3	432..502	CDD:214495
		LRR 6	526..549
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900