DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr14 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	200	Identity:	49/200 - (24%)
Similarity:	78/200 - (39%)	Gaps:	42/200 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ISTQLSSSVYLHCRV-NDLQGK----TVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWK 143
            ::.:....|.|.|.| :.:.|:    .|.|.:........|.||.:....|..|:......:...
Mouse    35 VTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKAS 99

  Fly   144 LLIQFANERDEGPYECQVSSHPPLVL-----------LVYLTIIVPHVEILDERGSATPEKYYKA 197
            |.::.....|:|.|||:|     |:|           .|:|||..|      ...:.||.:|.:|
Mouse   100 LRLEQVRSEDQGWYECKV-----LMLDQQYDTFHNGSWVHLTINAP------PTFTETPPQYIEA 153

  Fly   198 --GSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDT 260
              |.:|.:.|  :...:|...:||.....||       |.|.|..:..|    .|.:.:.:|:|.
Mouse   154 KEGGSITMTC--TAFGNPKPIVTWLKEGTLL-------GASAKYQVSDG----SLTVTSVSREDR 205

  Fly   261 GNYTC 265
            |.|||
Mouse   206 GAYTC 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	19/83 (23%)
		Ig	84..169	CDD:299845	20/89 (22%)
		IG_like	191..279	CDD:214653	21/76 (28%)
		Ig	201..274	CDD:143165	17/64 (27%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	18/73 (25%)
		I-set	141..227	CDD:369462	22/82 (27%)
		Ig	231..323	CDD:386229
		Ig	<355..416	CDD:386229
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900